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BioLiP Library
Download all results in tab-seperated text for 9 receptor-ligand interactions, whose format is explained at readme.txt.
  • Hover over PDB to view the title of the structure. Click PDB to view the structure at the RCSB PDB database. Resolution -1.00 means the resolution is unavailable, e.g., for NMR structures.
  • Click Site # to view the binding site structure. Hover over Site # to view the binding residues.
  • Hover over Ligand to view the full ligand name. Click Ligand to view the 2D diagram and other detail information of the ligand.
  • Hover over EC number to view the full name of enzymatic activity.
  • Hover over GO terms to view all GO terms.
  • Hover over UniProt to view the protein name.

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    # PDB
    (Resolution Å)     		Site # Ligand EC number GO terms UniProt PubMed Binding
    affinity
    1 2z5x:A (2.2) BS02 HRM 1.4.3.21
    1.4.3.4    		 GO:0005515 ... P21397 18391214 BindingDB: Ki=17nM
    2 2z5y:A (2.17) BS02 HRM 1.4.3.21
    1.4.3.4    		 GO:0005515 ... P21397 18391214 BindingDB: Ki=17nM
    3 3anr:A (2.6) BS01 HRM 2.7.11.23
    2.7.12.1    		 GO:0004672 ... Q13627 20981014 PDBbind: -logKd/Ki=6.46, IC50=0.35uM
    BindingDB: IC50=80nM, Ki=33nM
    4 3anr:B (2.6) BS01 HRM 2.7.11.23
    2.7.12.1    		 GO:0004672 ... Q13627 20981014 BindingDB: IC50=80nM, Ki=33nM
    5 3anr:C (2.6) BS01 HRM 2.7.11.23
    2.7.12.1    		 GO:0004672 ... Q13627 20981014 BindingDB: IC50=80nM, Ki=33nM
    6 3anr:D (2.6) BS01 HRM 2.7.11.23
    2.7.12.1    		 GO:0004672 ... Q13627 20981014 BindingDB: IC50=80nM, Ki=33nM
    7 5y86:A (1.9) BS01 HRM 2.7.12.1 GO:0000242 ... O43781 29634919 MOAD: ic50=0.8uM
    PDBbind: -logKd/Ki=6.10, IC50=0.8uM
    BindingDB: IC50=800nM
    8 7x9d:A (3.08) BS01 HRM 2.1.1.37 GO:0008168 ... Q9UBC3 37188336
    9 7x9d:D (3.08) BS01 HRM 2.1.1.37 GO:0008168 ... Q9UBC3 37188336
    Reference:
    • Chengxin Zhang, Xi Zhang, Peter L Freddolino, and Yang Zhang. BioLiP2: an updated structure database for biologically relevent ligand-protein interactions, Nucleic Acids Research, gkad630 (2023)(download the PDF file).
    • Jianyi Yang, Ambrish Roy, and Yang Zhang. BioLiP: a semi-manually curated database for biologically relevant ligand-protein interactions, Nucleic Acids Research, 41: D1096-D1103 (2013) (download the PDF file).

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