BioLiP

Structure of PDB 6nca Chain M

Receptor sequence

>6ncaM (length=275) Species: 9606 (Homo sapiens) [Search protein sequence]

GSHSMRYFFTSVSRPGRGEPRFIAVGYVDDTQFVRFDSDAASQRMEPRAP
WIEQEGPEYWDGETRKVKAHSQTHRVDLGTLRGYYNQSEAGSHTVQRMYG
CDVGSDWRFLRGYHQYAYDGKDYIALKEDLRSWTAADMAAQTTKHKWEAA
HVAEQLRAYLEGTCVEWLRRYLENGKETLQRTDAPKTHMTHHAVSDHEAT
LRCWALSFYPAEITLTWQRDGEDQTQDTELVETRPAGDGTFQKWAAVVVP
SGQEQRYTCHVQHEGLPKPLTLRWE

3D structure

PDB

6nca CDR3 alpha drives selection of the immunodominant Epstein Barr virus (EBV) BRLF1-specific CD8 T cell receptor repertoire in primary infection.

Chain

Resolution

3.3 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	M	Y7 E63 K66 H70 T73 D77 T80 L81 Y99 T143 W147 Q155 Y159 T163	Y7 E63 K66 H70 T73 D77 T80 L81 Y99 T143 W147 Q155 Y159 T163

External links

PDB	RCSB:6nca, PDBe:6nca, PDBj:6nca
PDBsum	6nca
PubMed	31765434
UniProt	P04439\|HLAA_HUMAN HLA class I histocompatibility antigen, A alpha chain (Gene Name=HLA-A)

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