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Structure of PDB 4i42 Chain K

Receptor sequence >4i42K (length=285) Species: 83333 (Escherichia coli K-12) [Search protein sequence] MIYPDEAMLYAPVEWHDCSEGFEDIRYEKSTDGIAKITINRPQVRNAFRP LTVKEMIQALADARYDDNIGVIILTGAGDKAFCSGGDQKVRGDYGGYKDD SGVHHLNVLDFQRQIRTCPKPVVAMVAGYSIGGGHVLHMMCDLTIAADNA IFGQTGPKVGSFDGGWGASYMARIVGQKKAREIWFLCRQYDAKQALDMGL VNTVVPLADLEKETVRWCREMLQNSPMALRCLKAALNADCDGQAGLQELA GNATMLFYMTEEGQEGRNAFNQKRQPDFSKFKRNP

3D structure PDB 4i42 Structural basis of the induced-fit mechanism of 1,4-dihydroxy-2-naphthoyl coenzyme A synthase from the crotonase fold superfamily Chain K Resolution 1.848 Å 3D structure Catalytic site residues are labeled in the structure [Spin on] [Spin off] [Reset orientation] [High quality] [Low quality] [White background] [Black background] [Download] [Download structure with residue number starting from 1]

Enzymatic activity Catalytic site (original residue number in PDB) G86 R91 Y97 H105 L109 G133 V136 G156 S161 D163 G164 A250 Y258 Catalytic site (residue number reindexed from 1) G86 R91 Y97 H105 L109 G133 V136 G156 S161 D163 G164 A250 Y258 Enzyme Commision number 4.1.3.36: 1,4-dihydroxy-2-naphthoyl-CoA synthase.

Interaction with ligand Site # Ligand Ligand chain Binding residues on receptor (original residue number in PDB) Binding residues on receptor (residue number reindexed from 1) Binding affinity BS01 1HA K T254 F270 K273 T254 F270 K273 BS02 1HA K V44 R45 S84 G85 G86 D87 Q88 K89 Y97 V108 Y129 G133 T155 V159 S161 V44 R45 S84 G85 G86 D87 Q88 K89 Y97 V108 Y129 G133 T155 V159 S161

Gene Ontology Molecular Function GO:0003824 catalytic activity GO:0005515 protein binding GO:0008935 1,4-dihydroxy-2-naphthoyl-CoA synthase activity GO:0016829 lyase activity GO:0071890 bicarbonate binding

	Biological Process
GO:0009234	menaquinone biosynthetic process

	Cellular Component
GO:0005829	cytosol

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