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BioLiP

Structure of PDB 4j8u Chain H

Receptor sequence
>4j8uH (length=95) Species: 8355 (Xenopus laevis) [Search protein sequence]
KTRKESYAIYVYKVLKQVHPDTGISSKAMSIMNSFVNDVFERIAGEASRL
AHYNKRSTITSREIQTAVRLLLPGELAKHAVSEGTKAVTKYTSAK
3D structure
PDB4j8u Novel metal(II) arene 2-pyridinecarbothioamides: a rationale to orally active organometallic anticancer agents
ChainH
Resolution2.38 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 dna H K31 S33 Y37 K4 S6 Y10
BS02 dna H K28 T29 S52 S53 R83 S84 T85 K1 T2 S25 S26 R56 S57 T58
BS03 ELJ H K31 E68 K4 E41
BS04 ELJ H E102 H106 E75 H79
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0030527 structural constituent of chromatin
GO:0046982 protein heterodimerization activity
Cellular Component
GO:0000786 nucleosome
GO:0005634 nucleus
GO:0005694 chromosome

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Molecular Function

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Cellular Component
External links
PDB RCSB:4j8u, PDBe:4j8u, PDBj:4j8u
PDBsum4j8u
PubMed
UniProtP02281|H2B11_XENLA Histone H2B 1.1

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