Structure of PDB 1gmo Chain H

Receptor sequence

>1gmoH (length=171) Species: 9606 (Homo sapiens) [Search protein sequence]

TIHEFKKSAKTTLIKIDPALKIKTKKVNTADQCADRCTRNKGLPFTCKAF
VFDKARKQCLWFPFNSMSSGVKKEFGHEFDLYENKDYIRNCIIGKGRSYK
GTVSITKSGIKCQPWSSMIPHEHSFLPSSYRGKDLQENYCRNPRGEEGGP
WCFTSNPEVRYEVCDIPQCSE

3D structure

PDB

1gmo Crystal Structures of Nk1-Heparin Complexes Reveal the Basis for Nk1 Activity and Enable Engineering of Potent Agonists of the met Receptor

Chain

Resolution

3.0 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	SGN	H	K60 T61 K62 K63	K23 T24 K25 K26
BS02	SGN	H	K78 G79	K41 G42
BS03	SO4	H	G169 D171 Q173	G132 D134 Q136

External links

PDB	RCSB:1gmo, PDBe:1gmo, PDBj:1gmo
PDBsum	1gmo
PubMed	11597998
UniProt	P14210\|HGF_HUMAN Hepatocyte growth factor (Gene Name=HGF)

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