BioLiP

Structure of PDB 7k5e Chain G

Receptor sequence

>7k5eG (length=156) Species: 208964 (Pseudomonas aeruginosa PAO1) [Search protein sequence]

MKGDKKVIQHLNKILGNELIAINQYFLHSRMWNDWGLKRLGAHEYHESID
EMKHADKLIERILFLEGLPNLQDLGKLLIGENTQEMLQCDLNLELKATKD
LREAIVHCEQVHDYVSRDLLKDILESEEEHIDYLETQLGLIQKVGLENYL
QSHMHE

3D structure

PDB

7k5e Small Molecule Inhibitors of the Bacterioferritin (BfrB)-Ferredoxin (Bfd) Complex Kill Biofilm-Embedded Pseudomonas aeruginosa Cells.

Chain

Resolution

1.75 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

1.16.3.1: ferroxidase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	VXM	G	L68 P69 N70 L71	L68 P69 N70 L71	MOAD: Kd=7uM

Gene Ontology

	Molecular Function
GO:0004322	ferroxidase activity
GO:0005506	iron ion binding
GO:0008199	ferric iron binding
GO:0015093	ferrous iron transmembrane transporter activity
GO:0016491	oxidoreductase activity
GO:0020037	heme binding
GO:0046872	metal ion binding

	Biological Process
GO:0006826	iron ion transport
GO:0006879	intracellular iron ion homeostasis
GO:0006880	intracellular sequestering of iron ion
GO:0034755	iron ion transmembrane transport

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0070288	ferritin complex

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Molecular Function

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Biological Process

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Cellular Component

PDB	RCSB:7k5e, PDBe:7k5e, PDBj:7k5e
PDBsum	7k5e
PubMed	33269912
UniProt	Q9HY79