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Structure of PDB 4qz6 Chain G

Receptor sequence >4qz6G (length=241) Species: 559292 (Saccharomyces cerevisiae S288C) [Search protein sequence] GYDRHITIFSPEGRLYQVEYAFKATNQTNINSLAVRGKDCTVVISQKKVP DKLLDPTTVSYIFCISRTIGMVVNGPIPDARNAALRAKAEAAEFRYKYGY DMPCDVLAKRMANLSQIYTQRAYMRPLGVILTFVSVDEELGPSIYKTDPA GYYVGYKATATGPKQQEITTNLENHFKKSKIDHINEESWEKVVEFAITHM IDALGTEFSKNDLEVGVATKDKFFTLSAENIEERLVAIAEQ

3D structure PDB 4qz6 Bortezomib-Resistant Mutant Proteasomes: Structural and Biochemical Evaluation with Carfilzomib and ONX 0914. Chain G Resolution 2.9 Å 3D structure [Spin on] [Spin off] [Reset orientation] [High quality] [Low quality] [White background] [Black background] [Download] [Download structure with residue number starting from 1]

Enzymatic activity Enzyme Commision number 3.4.25.1: proteasome endopeptidase complex.

Interaction with ligand Site # Ligand Ligand chain Binding residues on receptor (original residue number in PDB) Binding residues on receptor (residue number reindexed from 1) Binding affinity BS01 MG G T8 R122 A123 M125 T7 R121 A122 M124

Gene Ontology Molecular Function GO:0003674 molecular_function GO:0005515 protein binding

	Biological Process
GO:0006511	ubiquitin-dependent protein catabolic process
GO:0010499	proteasomal ubiquitin-independent protein catabolic process
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051603	proteolysis involved in protein catabolic process

	Cellular Component
GO:0000502	proteasome complex
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005739	mitochondrion
GO:0005839	proteasome core complex
GO:0019773	proteasome core complex, alpha-subunit complex

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