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Structure of PDB 6plz Chain E

Receptor sequence >6plzE (length=345) Species: 7955 (Danio rerio) [Search protein sequence] PMPPSEFLDKLMGKVSGYDARIRPNFKGPPVNVTCNIFINSFGSIAETTM DYRVNIFLRQQWNDPRLAYSEYPDDSLDLDPSMLDSIWKPDLFFANEKGA NFHEVTTDNKLLRISKNGNVLYSIRITLVLACPMDLKNFPMDVQTCIMQL ESFGYTMNDLIFEWDEKGAVQVADGLTLPQFILKEEKDLRYCTKHYNTGK FTCIEARFHLERQMGYYLIQMYIPSLLIVILSWVSFWINMDAAPARVGLG ITTVLTMTTQSSGSRASLPKVSYVKAIDIWMAVCLLFVFSALLEYAAVNF IARQHEEMRKLFISRAKRIDTVSRVAFPLVFLIFNIFYWITYKII

3D structure PDB 6plz Mechanism of gating and partial agonist action in the glycine receptor. Chain E Resolution 3.0 Å 3D structure [Spin on] [Spin off] [Reset orientation] [High quality] [Low quality] [White background] [Black background] [Download] [Download structure with residue number starting from 1]

Enzymatic activity Enzyme Commision number ?

Interaction with ligand Site # Ligand Ligand chain Binding residues on receptor (original residue number in PDB) Binding residues on receptor (residue number reindexed from 1) Binding affinity BS01 ABU E F175 F223 F153 F201 BS02 ABU E R81 S145 R59 S123

Gene Ontology Molecular Function GO:0004888 transmembrane signaling receptor activity GO:0005216 monoatomic ion channel activity GO:0005230 extracellular ligand-gated monoatomic ion channel activity GO:0016594 glycine binding GO:0016934 extracellularly glycine-gated chloride channel activity GO:0022824 transmitter-gated monoatomic ion channel activity

	Biological Process
GO:0006811	monoatomic ion transport
GO:0006821	chloride transport
GO:0034220	monoatomic ion transmembrane transport

	Cellular Component
GO:0005886	plasma membrane
GO:0016020	membrane
GO:0045211	postsynaptic membrane

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