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Structure of PDB 8qqu Chain C

Receptor sequence >8qquC (length=519) Species: 562 (Escherichia coli) [Search protein sequence] REITPVNIEEELKSSYLDYAMSVIVGRALPDVRDGLKPVHRRVLYAMNVL GNDWNKAYKKSARVVGDVIGKYHPHGDSAVYDTIVRMAQPFSLRYMLVDG QGNFGSIDGDSAAAMRFTEIRLAKIAHELMADLEKETVDFVDNYDGTEKI PDVMPTKIPNLLVNGSSGIAVGMATNIPPHNLTEVINGCLAYIDDEDISI EGLMEHIPGPDFPTAAIINGRRGIEEAYRTGRGKVYIRARAEVEVDAKTG RETIIVHEIPYQVNKARLIEKIAELVKEKRVEGISALRDESDKDGMRIVI EVKRDAVGEVVLNNLYSQTQLQVSFGINMVALHHGQPKIMNLKDIIAAFV RHRREVVTRRTIFELRKARDRAHILEALAVALANIDPIIELIRHAPTPAE AKTALVANPWQLGNVAAMLERAGDDAARPEWLEPEFGVRDGLYYLTEQQA QAILDLRLQKLTGLEHEKLLDEYKELLDQIAELLRILGSADRLMEVIREE LELVREQFGDKRRTEITAN

3D structure PDB 8qqu Structural basis of DNA crossover capture by E. coli DNA gyrase Chain C Resolution 2.9 Å 3D structure [Spin on] [Spin off] [Reset orientation] [High quality] [Low quality] [White background] [Black background] [Download] [Download structure with residue number starting from 1]

Enzymatic activity Enzyme Commision number 5.6.2.2: DNA topoisomerase (ATP-hydrolyzing).

Interaction with ligand Site # Ligand Ligand chain Binding residues on receptor (original residue number in PDB) Binding residues on receptor (residue number reindexed from 1) Binding affinity BS01 dna C Y21 I174 V176 K239 K276 S329 Y16 I169 V171 K234 K271 S324 BS02 dna C R32 H45 H78 H80 T88 R91 S172 I174 R272 R27 H40 H73 H75 T83 R86 S167 I169 R267

Gene Ontology Molecular Function GO:0003677 DNA binding GO:0003916 DNA topoisomerase activity GO:0003918 DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) activity GO:0005515 protein binding GO:0005524 ATP binding GO:0008094 ATP-dependent activity, acting on DNA GO:0034335 DNA negative supercoiling activity GO:0042802 identical protein binding

	Biological Process
GO:0006259	DNA metabolic process
GO:0006261	DNA-templated DNA replication
GO:0006265	DNA topological change
GO:0006351	DNA-templated transcription
GO:0009410	response to xenobiotic stimulus
GO:0046677	response to antibiotic
GO:0051276	chromosome organization
GO:2000104	negative regulation of DNA-templated DNA replication

	Cellular Component
GO:0005694	chromosome
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0009330	DNA topoisomerase type II (double strand cut, ATP-hydrolyzing) complex
GO:0016020	membrane

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