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Structure of PDB 8ovh Chain C

Receptor sequence >8ovhC (length=400) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] MPSHFDTVQLHAGQENSRAVPIYATTSYNPTSNVLEERIAALEGGAAALA VSSGQAAQTLAIQGLAHTGDNIVSTSYLYGGTYNQFKISFKRFGIEARFV EGDNPEEFEKVFDERTKAVYLETIGNPKYNVPDFEKIVAIAHKHGIPVVV DNTFGAGGYFCQPIKYGADIVTHSATKWIGGHGTTIGGIIVDSGKFPWKD YPEKFPQFSQPAEGYHGTIYNEAYGNLAYIVHVRTELLRDLGPLMNPFAS FLLLQGVETLSLRAERHGENALKLAKWLEQSPYVSWVSYPGLASHSHHEN AKKYLSNGFGGVLSFGVKDLPNADKETDPFKLSGAQVVDNLKLASNLANV GDAKTLVIAPYFTTGVTKDLIRVSVGIEFIDDIIADFQQSFETVFAGQKP

3D structure PDB 8ovh Enzymatic Synthesis of l-Methionine Analogues and Application in a Methyltransferase Catalysed Alkylation Cascade. Chain C Resolution 2.171 Å 3D structure [Spin on] [Spin off] [Reset orientation] [High quality] [Low quality] [White background] [Black background] [Download] [Download structure with residue number starting from 1]

Enzymatic activity Enzyme Commision number 2.5.1.47: cysteine synthase. 2.5.1.49: O-acetylhomoserine aminocarboxypropyltransferase.

Interaction with ligand Site # Ligand Ligand chain Binding residues on receptor (original residue number in PDB) Binding residues on receptor (residue number reindexed from 1) Binding affinity BS01 PLP C G86 Q87 Q90 Y111 D183 S206 T208 K209 G54 Q55 Q58 Y79 D151 S174 T176 K177

Gene Ontology Molecular Function GO:0003961 O-acetylhomoserine aminocarboxypropyltransferase activity GO:0004124 cysteine synthase activity GO:0016740 transferase activity GO:0016765 transferase activity, transferring alkyl or aryl (other than methyl) groups GO:0030170 pyridoxal phosphate binding GO:0051009 O-acetylhomoserine sulfhydrylase activity

	Biological Process
GO:0000103	sulfate assimilation
GO:0006520	amino acid metabolic process
GO:0006535	cysteine biosynthetic process from serine
GO:0006555	methionine metabolic process
GO:0009086	methionine biosynthetic process
GO:0019344	cysteine biosynthetic process
GO:0019346	transsulfuration
GO:0071266	'de novo' L-methionine biosynthetic process
GO:0071269	L-homocysteine biosynthetic process

	Cellular Component
GO:0005737	cytoplasm
GO:0005886	plasma membrane

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