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BioLiP

Structure of PDB 7ukh Chain C

Receptor sequence
>7ukhC (length=203) Species: 9606 (Homo sapiens) [Search protein sequence]
GVAAWLPFARAAAIGWMPVASGPMPAPPRQERKRTQDALIVLNVSGTRFQ
TWQDTLERYPDTLLGSSERDFFYHPETQQYFFDRDPDIFRHILNFYRTGK
LHYPRHECISAYDEELAFFGLIPEIIGDCCYEEYKDRRRENAERLQDDAD
QKKARLARIRAAKSGSANAYMQSKRNGSSFETQHHHLLHCLEKTTNHEFV
DEQ
3D structure
PDB7ukh Activation and closed-state inactivation mechanisms of the human voltage-gated K V 4 channel complexes.
ChainC
Resolution2.33 Å
3D
structure
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Enzymatic activity
Enzyme Commision number ?
Interaction with ligand
Site
#
Ligand Ligand
chain
Binding residues on receptor
(original residue number in PDB)
Binding residues on receptor
(residue number reindexed from 1)
Binding affinity
BS01 ZN C H105 C132 H102 C129
Gene Ontology
Molecular Function
GO:0005216 monoatomic ion channel activity
GO:0005249 voltage-gated potassium channel activity
Biological Process
GO:0006811 monoatomic ion transport
GO:0006813 potassium ion transport
GO:0051260 protein homooligomerization
GO:0055085 transmembrane transport
Cellular Component
GO:0008076 voltage-gated potassium channel complex
GO:0016020 membrane

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Cellular Component
External links
PDB RCSB:7ukh, PDBe:7ukh, PDBj:7ukh
PDBsum7ukh
PubMed35597238
UniProtQ9NZV8|KCND2_HUMAN A-type voltage-gated potassium channel KCND2 (Gene Name=KCND2)

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