Structure of PDB 5dn2 Chain C

Receptor sequence

>5dn2C (length=156) Species: 9606 (Homo sapiens) [Search protein sequence]

MFQCNVPLGMESGRIANEQISASSTYSDGRWTPQQSRLHGDDNGWTPNLD
SNKEYLQVDLRFLTMLTAIATQGAISRETQNGYYVKSYKLEVSTNGEDWM
VYRHGKNHKVFQANNDATEVVLNKLHAPLLTRFVRIRPQTWHSGIALRLE
LFGCRV

3D structure

PDB

5dn2 Structural studies of neuropilin-2 reveal a zinc ion binding site remote from the vascular endothelial growth factor binding pocket.

Chain

Resolution

1.95 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	C	R303 E351	R30 E78
BS02	peptide	C	Y299 W304 T319 D323 S349 E351 T352 Y356 G417 I418	Y26 W31 T46 D50 S76 E78 T79 Y83 G144 I145

External links

PDB	RCSB:5dn2, PDBe:5dn2, PDBj:5dn2
PDBsum	5dn2
PubMed	26991001
UniProt	O60462\|NRP2_HUMAN Neuropilin-2 (Gene Name=NRP2)

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