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Structure of PDB 4wx7 Chain C

Receptor sequence >4wx7C (length=204) Species: 31545 (Human adenovirus D8) [Search protein sequence] SGSSEQELAAIVRDLGCGPYFLGTHDKRFPGFLAGNKLACAIVNTAGRET GGVHWLAFGWNPRSRTCYMFDPFGFSDRRLKQIYSFEYEAMLRRSALALS PDRCLSLEQSTQTVQGPDSAACGLFCCMFLHAFVHWPDRPMDGNPTMNLL TGVPNGMLQSPQVLPTLRRNQEKLYRFLAHHSPYFRSHRAAIEHATAFDK MKQL

3D structure PDB 4wx7 Structure-based design and optimization of potent inhibitors of the adenoviral protease. Chain C Resolution 2.4 Å 3D structure Catalytic site residues are labeled in the structure [Spin on] [Spin off] [Reset orientation] [High quality] [Low quality] [White background] [Black background] [Download] [Download structure with residue number starting from 1]

Enzymatic activity Catalytic site (original residue number in PDB) H54 D71 Q115 C122 Catalytic site (residue number reindexed from 1) H54 D71 Q115 C122 Enzyme Commision number 3.4.22.39: adenain.

Interaction with ligand Site # Ligand Ligand chain Binding residues on receptor (original residue number in PDB) Binding residues on receptor (residue number reindexed from 1) Binding affinity BS01 peptide C D77 E89 L92 R93 R103 C104 L105 L107 E108 Q109 S110 T111 Q112 M141 D142 M147 G152 D77 E89 L92 R93 R103 C104 L105 L107 E108 Q109 S110 T111 Q112 M141 D142 M147 G152 BS02 3VJ C G2 S3 S4 E5 T24 H25 D26 N44 G47 R48 G51 G52 V53 H54 W55 C122 G2 S3 S4 E5 T24 H25 D26 N44 G47 R48 G51 G52 V53 H54 W55 C122

Gene Ontology Molecular Function GO:0003677 DNA binding GO:0004197 cysteine-type endopeptidase activity GO:0008234 cysteine-type peptidase activity

	Biological Process
GO:0006508	proteolysis

	Cellular Component
GO:0042025	host cell nucleus
GO:0044423	virion component

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