Structure of PDB 4awh Chain C

Receptor sequence

>4awhC (length=193) Species: 641501 (Influenza A virus (A/California/04/2009(H1N1))) [Search protein sequence]

MAMEDFVRQCFNPMIVELAEKAMKEYGEDPKIETNKFAAICTHLEVCFMY
SDFHFIDERGESIIVESALLKHRFEIIEGRDRIMAWTVVNSICNTTGVEK
PKFLPDLYDYKENRFIEIGVTRREVHIYYLEKANKIKSEKTHIHIFSFTG
EEMATKADYTLDEESRARIKTRLFTIRQEMASRSLWDSFRQSE

3D structure

PDB

4awh Structural Analysis of Specific Metal Chelating Inhibitor Binding to the Endonuclease Domain of Influenza Ph1N1 (2009) Polymerase.

Chain

Resolution

2.05 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

3.1.-.-

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	MN	C	H41 D108 E119 I120	H43 D106 E117 I118
BS02	MN	C	E80 D108	E78 D106
BS03	U5P	C	Y24 K34 H41 D108 E119 K134	Y26 K36 H43 D106 E117 K132

Gene Ontology

	Molecular Function
GO:0003723	RNA binding

	Biological Process
GO:0039694	viral RNA genome replication

View graph for
Molecular Function

View graph for
Biological Process

External links

PDB	RCSB:4awh, PDBe:4awh, PDBj:4awh
PDBsum	4awh
PubMed	22876177
UniProt	C3W5S0

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