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Structure of PDB 1zos Chain C

Receptor sequence >1zosC (length=230) Species: 171101 (Streptococcus pneumoniae R6) [Search protein sequence] MKIGIIAAMPEELAYLVQHLDNTQEQVVLGNTYHTGTIASHEVVLVESGI GKVMSAMSVAILADHFQVDALINTGSAGAVAEGIAVGDVVIADKLAYHDV DVTAFGYAYGQMAQQPLYFESDKTFVAQIQESLSQLDQNWHLGLIATGDS FVAGNDKIEAIKSHFPEVLAVEMEGAAIAQAAHTLNLPVLVIRAMSDNAN HEANIFFDEFIIEAGRRSAQVLLAFLKALD

3D structure PDB 1zos Structure and inhibition of a quorum sensing target from Streptococcus pneumoniae. Chain C Resolution 1.6 Å 3D structure [Spin on] [Spin off] [Reset orientation] [High quality] [Low quality] [White background] [Black background] [Download] [Download structure with residue number starting from 1]

Enzymatic activity Enzyme Commision number 3.2.2.9: adenosylhomocysteine nucleosidase.

Interaction with ligand Site # Ligand Ligand chain Binding residues on receptor (original residue number in PDB) Binding residues on receptor (residue number reindexed from 1) Binding affinity BS01 MTM C I50 S76 A77 G78 F151 V152 E172 M173 E174 S196 D197 A199 F207 I50 S76 A77 G78 F151 V152 E172 M173 E174 S196 D197 A199 F207 MOAD: Ki=1uM

Gene Ontology Molecular Function GO:0003824 catalytic activity GO:0008782 adenosylhomocysteine nucleosidase activity GO:0008930 methylthioadenosine nucleosidase activity GO:0016798 hydrolase activity, acting on glycosyl bonds

	Biological Process
GO:0009086	methionine biosynthetic process
GO:0009116	nucleoside metabolic process
GO:0009164	nucleoside catabolic process
GO:0019284	L-methionine salvage from S-adenosylmethionine
GO:0019509	L-methionine salvage from methylthioadenosine

	Cellular Component
GO:0005829	cytosol

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