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Structure of PDB 1eth Chain C

Receptor sequence >1ethC (length=448) Species: 9823 (Sus scrofa) [Search protein sequence] SEVCFPRLGCFSDDAPWAGIVQRPLKILPWSPKDVDTRFLLYTNQNQNNY QELVADPSTITNSNFRMDRKTRFIIHGFIDKGEEDWLSNICKNLFKVESV NCICVDWKGGSRTGYTQASQNIRIVGAEVAYFVEVLKSSLGYSPSNVHVI GHSLGSHAAGEAGRRTNGTIERITGLDPAEPCFQGTPELVRLDPSDAKFV DVIHTDAAPIIPNLGFGMSQTVGHLDFFPNGGKQMPGCQKNILSQIVDID GIWEGTRDFVACNHLRSYKYYADSILNPDGFAGFPCDSYNVFTANKCFPC PSEGCPQMGHYADRFPGKTNGVSQVFYLNTGDASNFARWRYKVSVTLSGK KVTGHILVSLFGNEGNSRQYEIYKGTLQPDNTHSDEFDSDVEVGDLQKVK FIWYNVINPTLPRVGASKITVERNDGKVYDFCSQETVREEVLLTLNPC

3D structure PDB 1eth Lipase activation by nonionic detergents. The crystal structure of the porcine lipase-colipase-tetraethylene glycol monooctyl ether complex. Chain C Resolution 2.8 Å 3D structure Catalytic site residues are labeled in the structure [Spin on] [Spin off] [Reset orientation] [High quality] [Low quality] [White background] [Black background] [Download] [Download structure with residue number starting from 1]

Enzymatic activity Catalytic site (original residue number in PDB) F78 S153 L154 D177 H264 Catalytic site (residue number reindexed from 1) F78 S153 L154 D177 H264 Enzyme Commision number 3.1.1.3: triacylglycerol lipase.

Interaction with ligand Site # Ligand Ligand chain Binding residues on receptor (original residue number in PDB) Binding residues on receptor (residue number reindexed from 1) Binding affinity BS01 BMA C R164 R165 R164 R165 BS02 CA C E188 R191 D193 D196 E188 R191 D193 D196 BS03 C8E C I79 F216 W253 I79 F216 W253 BS04 C8E C H76 G77 F78 I79 D80 W86 H152 S153 R257 H76 G77 F78 I79 D80 W86 H152 S153 R257

Gene Ontology Molecular Function GO:0004806 triacylglycerol lipase activity GO:0016298 lipase activity GO:0016787 hydrolase activity GO:0046872 metal ion binding GO:0047376 all-trans-retinyl-palmitate hydrolase, all-trans-retinol forming activity GO:0052689 carboxylic ester hydrolase activity

	Biological Process
GO:0006629	lipid metabolic process
GO:0016042	lipid catabolic process
GO:0042572	retinol metabolic process

	Cellular Component
GO:0005576	extracellular region
GO:0005615	extracellular space

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