BioLiP

Structure of PDB 1d4c Chain C

Receptor sequence

>1d4cC (length=568) Species: 70863 (Shewanella oneidensis) [Search protein sequence]

EVLADFHGEMGGCDSCHVSDKGGVTNDNLTHENGQCVSCHGDLKELAAAA
PKDKVSPHKSHLIGEIACTSCHKGHEKSVAYCDACHSFGFDMPFGGKWER
KFVPVDADKAAQDKAIAAGVKETTDVVIIGSGGAGLAAAVSARDAGAKVI
LLEKEPIPGGNTKLAAGGMNAAETKPQAKLGIEDKKQIMIDDTMKGGRNI
NDPELVKVLANNSSDSIDWLTSMGADMTDVGRMGGASVNRSHRPTGGAGV
GAHVAQVLWDNAVKRGTDIRLNSRVVRILEDASGKVTGVLVKGEYTGYYV
IKADAVVIAAGGFAKNNERVSKYDPKLKGFKATNHPGATGDGLDVALQAG
AATRDLEYIQAHPTYSPAGGVMITEAVRGNGAIVVNREGNRFMNEITTRD
KASAAILQQKGESAYLVFDDSIRKSLKAIEGYVHLNIVKEGKTIEELAKQ
IDVPAAELAKTVTAYNGFVKSGKDAQFERPDLPRELVVAPFYALEIAPAV
HHTMGGLVIDTKAEVKSEKTGKPITGLYAAGEVTGGVHGANRLGGNAISD
IVTYGRIAGASAAKFAKD

3D structure

PDB

1d4c Structure and mechanism of the flavocytochrome c fumarate reductase of Shewanella putrefaciens MR-1.

Chain

Resolution

2.9 Å

3D
structure

Catalytic site residues are labeled in the structure
[Spin on]
[Spin off]
[Reset orientation]

[High quality]
[Low quality]

[White background]
[Black background]

[Download]
[Download structure with residue number starting from 1]

Enzymatic activity

Catalytic site (original residue number in PDB)	M235 Q362 H364 M374 E377 R380 R401 H503 H504 R544
Catalytic site (residue number reindexed from 1)	M233 Q360 H362 M372 E375 R378 R399 H501 H502 R542
Enzyme Commision number	1.3.2.4: fumarate reductase (cytochrome).

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)
BS01	HEC	C	R200 Y325 Y360	R198 Y323 Y358
BS02	HEC	C	S62 H63 Y83 C84 C87 H88 F90 L166 A168 H337 V373 G433 Y434 L437	S60 H61 Y81 C82 C85 H86 F88 L164 A166 H335 V371 G431 Y432 L435
BS03	HEC	C	H42 D44 L45 L48 P59 H60 C70 C73 H74 D93 M94	H40 D42 L43 L46 P57 H58 C68 C71 H72 D91 M92
BS04	HEC	C	A6 G14 C15 C18 H19 K23 G24 V26 K75 G76 H77 Y297	A4 G12 C13 C16 H17 K21 G22 V24 K73 G74 H75 Y295
BS05	HEC	C	L5 F8 H9 M12 Q37 C38 C41 H42 H74	L3 F6 H7 M10 Q35 C36 C39 H40 H72
BS06	FAD	C	I131 G132 G134 A136 L154 E155 K156 G162 N163 T164 L166 A167 G169 G170 R276 V277 A312 T335 H337 D343 M374 H503 H504 G533 E534 R544 G547 A549 I550 I553	I129 G130 G132 A134 L152 E153 K154 G160 N161 T162 L164 A165 G167 G168 R274 V275 A310 T333 H335 D341 M372 H501 H502 G531 E532 R542 G545 A547 I548 I551

Gene Ontology

	Molecular Function
GO:0010181	FMN binding
GO:0016491	oxidoreductase activity

View graph for
Molecular Function

PDB	RCSB:1d4c, PDBe:1d4c, PDBj:1d4c
PDBsum	1d4c
PubMed	10581551
UniProt	P83223\|FCCA_SHEON Fumarate reductase (cytochrome) (Gene Name=fccA)