BioLiP

Structure of PDB 1b7b Chain C

Receptor sequence

>1b7bC (length=307) Species: 1352 (Enterococcus faecium) [Search protein sequence]

GKKMVVALGGNAILSNDASAHAQQQALVQTSAYLVHLIKQGHRLIVSHGN
GPQVGNLLLQQQAADSEKNPAMPLDTCVAMTQGSIGYWLSNALNQELNKA
GIKKQVATVLTQVVVDPADEAFKNPTKPIGPFLTEAEAKEAMQAGAIFKE
DAGRGWRKVVPSPKPIDIHEAETINTLIKNDIITISCGGGGIPVVGQELK
GVEAVIDKDFASEKLAELVDADALVILTGVDYVCINYGKPDEKQLTNVTV
AELEEYKQAGHFAPGSMLPKIEAAIQFVESQPNKQAIITSLENLGSMSGD
EIVGTVV

3D structure

PDB

1b7b Carbamate kinase: New structural machinery for making carbamoyl phosphate, the common precursor of pyrimidines and arginine.

Chain

Resolution

2.8 Å

3D
structure

Catalytic site residues are labeled in the structure
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Enzymatic activity

Catalytic site (original residue number in PDB)	G11 N12 K128 K209 K271
Catalytic site (residue number reindexed from 1)	G10 N11 K127 K208 K270
Enzyme Commision number	2.7.2.2: carbamate kinase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	SO4	C	G10 G11 N12 G50 G52 K209	G9 G10 N11 G49 G51 K208

Gene Ontology

	Molecular Function
GO:0005524	ATP binding
GO:0008804	carbamate kinase activity
GO:0016301	kinase activity

	Biological Process
GO:0006525	arginine metabolic process
GO:0016310	phosphorylation
GO:0019546	arginine deiminase pathway

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol

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Molecular Function

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Cellular Component

PDB	RCSB:1b7b, PDBe:1b7b, PDBj:1b7b
PDBsum	1b7b
PubMed	10211841
UniProt	P0A2X8\|ARCC1_ENTFC Carbamate kinase 1 (Gene Name=arcC1)