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Structure of PDB 5yhv Chain B

Receptor sequence >5yhvB (length=387) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search protein sequence] TDRVALRAGVPPFYVMDVWLAAAERQRTHGDLVNLSAGQPSAGAPEPVRA AAAAALHLNQLGYSVALGIPELRDAIAADYQRRHGITVEPDAVVITTGSS GGFLLAFLACFDAGDRVAMASPGYPCYRNILSALGCEVVEIPCGPQTRFQ PTAQMLAEIDPPLRGVVVASPANPTGTVIPPEELAAIASWCDASDVRLIS DEVYHGLVYQGAPQTSCAWQTSRNAVVVNSFSKYYAMTGWRLGWLLVPTV LRRAVDCLTGNFTICPPVLSQIAAVSAFTPEATAEADGNLASYAINRSLL LDGLRRIGIDRLAPTDGAFYVYADVSDFTSDSLAFCSKLLADTGVAIAPG IDFDTARGGSFVRISFAGPSGDIEEALRRIGSWLPSQ

3D structure PDB 5yhv Crystal structure of an aminotransferase from Mycobacterium tuberculosis Chain B Resolution 2.7 Å 3D structure [Spin on] [Spin off] [Reset orientation] [High quality] [Low quality] [White background] [Black background] [Download] [Download structure with residue number starting from 1]

Enzymatic activity Enzyme Commision number 2.6.1.66: valine--pyruvate transaminase.

Interaction with ligand Site # Ligand Ligand chain Binding residues on receptor (original residue number in PDB) Binding residues on receptor (residue number reindexed from 1) Binding affinity BS01 PLP B Y64 I265 Y63 I264 BS02 PLP B G99 S100 S101 Y125 N174 D202 V204 Y205 S231 S233 K234 R242 G98 S99 S100 Y124 N173 D201 V203 Y204 S230 S232 K233 R241 BS03 AKG B Y81 H85 H206 T216 N230 Y80 H84 H205 T215 N229

Gene Ontology Molecular Function GO:0003824 catalytic activity GO:0008483 transaminase activity GO:0009042 valine-pyruvate transaminase activity GO:0030170 pyridoxal phosphate binding

	Biological Process
GO:0006520	amino acid metabolic process
GO:0009058	biosynthetic process

	Cellular Component
GO:0009274	peptidoglycan-based cell wall

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