Structure of PDB 4a1g Chain B

Receptor sequence

>4a1gB (length=149) Species: 9606 (Homo sapiens) [Search protein sequence]

DTPENVLQMLEAHMQSYKGNDPLGEWERYIQWVEENFPENKEYLITLLEH
LMKEFLDKKKYHNDPRFISYCLKFAEYNSDLHQFFEFLYNHGIGTLSSPL
YIAWAGHLEAQGELQHASAVLQRGIQNQAEPREFLQQQYRLFQTRLTET

3D structure

PDB

4a1g Structural Analysis Reveals Features of the Spindle Checkpoint Kinase Bub1-Kinetochore Subunit Knl1 Interaction.

Chain

Resolution

2.6 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

2.7.11.1: non-specific serine/threonine protein kinase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	B	E50 F75 Y78 N79 S80 D81 Q84 F88	E49 F74 Y77 N78 S79 D80 Q83 F87

Gene Ontology

	Biological Process
GO:0007094	mitotic spindle assembly checkpoint signaling

View graph for
Biological Process

External links

PDB	RCSB:4a1g, PDBe:4a1g, PDBj:4a1g
PDBsum	4a1g
PubMed	22331848
UniProt	O43683\|BUB1_HUMAN Mitotic checkpoint serine/threonine-protein kinase BUB1 (Gene Name=BUB1)

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