BioLiP

Structure of PDB 2yy7 Chain B

Receptor sequence

>2yy7B (length=312) Species: 262320 (Flavobacterium frigidimaris) [Search protein sequence]

MNPKILIIGACGQIGTELTQKLRKLYGTENVIASDIRKLNTDVVNSGPFE
VVNALDFNQIEHLVEVHKITDIYLMAALLSATAEKNPAFAWDLNMNSLFH
VLNLAKAKKIKKIFWPSSIAVFGPTTPKENTPQYTIMEPSTVYGISKQAG
ERWCEYYHNIYGVDVRSIRYPGLISWSTPPGGGTTDYAVDIFYKAIADKK
YECFLSSETKMPMMYMDDAIDATINIMKAPVEKIKIHSSYNLAAMSFTPT
EIANEIKKHIPEFTITYEPDFRQKIADSWPASIDDSQAREDWDWKHTFDL
ESMTKDMIEHLS

3D structure

PDB

2yy7 Crystal structure of UDP-galactose 4-epimerase-like L-threonine dehydrogenase belonging to the intermediate short-chain dehydrogenase-reductase superfamily

Chain

Resolution

2.061 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

1.1.1.103: L-threonine 3-dehydrogenase.

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	NAD	B	G9 C11 G12 Q13 I14 D35 I36 R37 V52 N53 A54 M75 A76 L93 P116 S118 Y143 K147 Y170 L173	G9 C11 G12 Q13 I14 D35 I36 R37 V52 N53 A54 M75 A76 L93 P116 S118 Y143 K147 Y170 L173
BS02	GOL	B	S80 S118 Y143 G183 T184 T185 W279	S80 S118 Y143 G183 T184 T185 W279

Gene Ontology

	Molecular Function
GO:0000166	nucleotide binding
GO:0008743	L-threonine 3-dehydrogenase activity

	Biological Process
GO:0006567	threonine catabolic process

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Molecular Function

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Biological Process

PDB	RCSB:2yy7, PDBe:2yy7, PDBj:2yy7
PDBsum	2yy7
PubMed	21078123
UniProt	Q8KZM4