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Structure of PDB 2bzd Chain B

Receptor sequence >2bzdB (length=601) Species: 1881 (Micromonospora viridifaciens) [Search protein sequence] GEPLYTEQDLAVNGREGFPNYRIPALTVTPDGDLLASYDGRPTGIDAPGP NSILQRRSTDGGRTWGEQQVVSAGQTTAPIKGFSDPSYLVDRETGTIFNF HVYSQRQGFAGSRPGTDPADPNVLHANVATSTDGGLTWSHRTITADITPD PGWRSRFAASGEGIQLRYGPHAGRLIQQYTIINAAGAFQAVSVYSDDHGR TWRAGEAVGVGMDANKTVELSDGRVLLNSRDSARSGYRKVAVSTDGGHSY GPVTIDRDLPDPTNNASIIRAFPDAPAGSARAKVLLFSNAASQTSRSQGT IRMSCDDGQTWPVSKVFQPGSMSYSTLTALPDGTYGLLYEPGTGIRYANF NLAWLGGICAPFTIPDVALEPGQQVTVPVAVTNQSGIAVPKPSLQLDASP DWQVQGSVEPLMPGRQAKGQVTITVPAGTTPGRYRVGATLRTSAGNASTT FTVTVGLLDQARMSIADVDSEETAREDGRASNVIDGNPSTFWHTEWSRAD APGYPHRISLDLGGTHTISGLQYTRRQNSANEQVADYEIYTSLNGTTWDG PVASGRFTTSLAPQRAVFPARDARYIRLVALSEQTGHKYAAVAELEVEGQ R

3D structure PDB 2bzd Galactose Recognition by the Carbohydrate-Binding Module of a Bacterial Sialidase. Chain B Resolution 2.0 Å 3D structure Catalytic site residues are labeled in the structure [Spin on] [Spin off] [Reset orientation] [High quality] [Low quality] [White background] [Black background] [Download] [Download structure with residue number starting from 1]

Enzymatic activity Catalytic site (original residue number in PDB) D92 A260 Y370 Catalytic site (residue number reindexed from 1) D46 A214 Y324 Enzyme Commision number 3.2.1.18: exo-alpha-sialidase.

Interaction with ligand Site # Ligand Ligand chain Binding residues on receptor (original residue number in PDB) Binding residues on receptor (residue number reindexed from 1) Binding affinity BS01 GAL B E522 H539 W542 R572 Y635 E476 H493 W496 R526 Y589 MOAD: Kd~1mM

Gene Ontology Molecular Function GO:0004308 exo-alpha-sialidase activity GO:0016798 hydrolase activity, acting on glycosyl bonds

	Biological Process
GO:0005975	carbohydrate metabolic process
GO:0006689	ganglioside catabolic process
GO:0009313	oligosaccharide catabolic process

	Cellular Component
GO:0005576	extracellular region
GO:0005737	cytoplasm
GO:0016020	membrane
GO:0043231	intracellular membrane-bounded organelle

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