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BioLiP

Structure of PDB 1a1c Chain B

Receptor sequence
>1a1cB (length=104) Species: 9606 (Homo sapiens) [Search protein sequence]
IQAEEWYFGKITRRESERLLLNAENPRGTFLVRESETTKGAYCLSVSDFD
NAKGLNVKHYKIRKLDSGGFYITSRTQFNSLQQLVAYYSKHADGLCHRLT
TVCP
3D structure
PDB1a1c Peptide ligands of pp60(c-src) SH2 domains: a thermodynamic and structural study.
ChainB
Resolution2.4 Å
3D
structure
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Enzymatic activity
Enzyme Commision number 2.7.10.2: non-specific protein-tyrosine kinase.
Interaction with ligand
Site
#		 Ligand Ligand
chain		 Binding residues on receptor
(original residue number in PDB)		 Binding residues on receptor
(residue number reindexed from 1)		 Binding affinity
BS01 peptide B R158 R178 S180 E181 T182 H204 Y205 K206 T218 G239 R13 R33 S35 E36 T37 H59 Y60 K61 T73 G94
External links
PDB RCSB:1a1c, PDBe:1a1c, PDBj:1a1c
PDBsum1a1c
PubMed9174343
UniProtP12931|SRC_HUMAN Proto-oncogene tyrosine-protein kinase Src (Gene Name=SRC)

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