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Structure of PDB 6h7o Chain A

Receptor sequence >6h7oA (length=290) Species: 9103 (Meleagris gallopavo) [Search protein sequence] AAKVMSLLMALVVLLIVAGNVLVIAAIGSTQRLQTLTNLFITSLACADLV VGLLVVPFGATLVVRGTWLWGSFLCELWTSLDVLCVTASIETLCVIAIDR YLAITSPFRYQSLMTRARAKVIICTVWAISALVSFLPIMMHWWRDEDPQA LKCYQDPGCCDFVTNRAYAIASSIISFYIPLLIMIFVYLRVYREAKEQIR KIDRASKRKTSRVMAMKEHKALKTLGIIMGVFTLCWLPFFLVNIVNVFNR DLVPDWLFVAFNWLGYANSAMNPIIYCRSPDFRKAFKRLL

3D structure PDB 6h7o Molecular basis for high-affinity agonist binding in GPCRs. Chain A Resolution 2.8 Å 3D structure [Spin on] [Spin off] [Reset orientation] [High quality] [Low quality] [White background] [Black background] [Download] [Download structure with residue number starting from 1]

Enzymatic activity Enzyme Commision number ?

Interaction with ligand Site # Ligand Ligand chain Binding residues on receptor (original residue number in PDB) Binding residues on receptor (residue number reindexed from 1) Binding affinity BS01 P32 A D121 V122 F201 T203 S211 S215 F306 F307 N310 N329 Y333 D82 V83 F162 T164 S172 S176 F239 F240 N243 N262 Y266 PDBbind-CN: -logKd/Ki=9.85,Kd=0.14nM BS02 2CV A W181 A206 Y207 W142 A167 Y168 BS03 2CV A R157 V160 R118 V121 BS04 2CV A L289 T300 L222 T233 BS05 2CV A I209 I213 I170 I174

Gene Ontology Molecular Function GO:0004930 G protein-coupled receptor activity GO:0004935 adrenergic receptor activity GO:0004940 beta1-adrenergic receptor activity

	Biological Process
GO:0007186	G protein-coupled receptor signaling pathway
GO:0007189	adenylate cyclase-activating G protein-coupled receptor signaling pathway
GO:0045823	positive regulation of heart contraction

	Cellular Component
GO:0016020	membrane

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