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Structure of PDB 5ycp Chain A

Receptor sequence >5ycpA (length=263) Species: 9606 (Homo sapiens) [Search protein sequence] LNPESADLRALAKHLYDSYIKSFPLTKAKARAILTGKTTDKSPFVIYDMN SLMMGEDKQSKEVAIRIFQGCQFRSVEAVQEITEYAKSIPGFVNLDLNDQ VTLLKYGVHEIIYTMLASLMNKDGVLISEGQGFMTREFLKSLRKPFGDFM EPKFEFAVKFNALELDDSDLAIFIAVIILSGDRPGLLNVKPIEDIQDNLL QALELQLKLNHPESSQLFAKLLQKMTDLRQIVTEHVQLLQVIKKTETDMS LHPLLQEIYKDLY

3D structure PDB 5ycp Structural Basis for the Enhanced Anti-Diabetic Efficacy of Lobeglitazone on PPAR gamma. Chain A Resolution 2.0 Å 3D structure [Spin on] [Spin off] [Reset orientation] [High quality] [Low quality] [White background] [Black background] [Download] [Download structure with residue number starting from 1]

Enzymatic activity Enzyme Commision number ?

Interaction with ligand Site # Ligand Ligand chain Binding residues on receptor (original residue number in PDB) Binding residues on receptor (residue number reindexed from 1) Binding affinity BS01 peptide A K301 L311 Q314 V315 L318 K319 L468 E471 K87 L97 Q100 V101 L104 K105 L254 E257 BS02 BRL A F282 C285 S289 H323 I341 H449 Y473 F68 C71 S75 H109 I127 H235 Y259 BindingDB: EC50=40nM,IC50=1.000000nM,Ki=8nM,Kd=0.145000nM

Gene Ontology Molecular Function GO:0003677 DNA binding GO:0004879 nuclear receptor activity

	Biological Process
GO:0006355	regulation of DNA-templated transcription

	Cellular Component
GO:0005634	nucleus

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