BioLiP

Structure of PDB 1t79 Chain A

Receptor sequence

>1t79A (length=250) Species: 9598 (Pan troglodytes) [Search protein sequence]

CQPIFLNVLEAIEPGVVCAGHDNNQPDSFAALLSSLNELGERQLVHVVKW
AKALPGFRNLHVDDQMAVIQYSWMGLMVFAMGWRSFTNVNSRMLYFAPDL
VFNEYRMHKSRMYSQCVRMRHLSQEFGWLQITPQEFLCMKALLLFSIIPV
DGLKNQKFFDELRMNYIKELDRIIACKRKNPTSCSRRFYQLTKLLDSVQP
IARELHQFTFDLLIKSHMVSVDFPEMMAEIISVQVPKILSGKVKPIYFHT

3D structure

PDB

1t79 Recognition and accommodation at the androgen receptor coactivator binding interface.

Chain

Resolution

1.8 Å

3D
structure

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Enzymatic activity

Enzyme Commision number

Interaction with ligand

Site #	Ligand	Ligand chain	Binding residues on receptor (original residue number in PDB)	Binding residues on receptor (residue number reindexed from 1)	Binding affinity
BS01	peptide	A	V716 K720 Q733 M734 I737 Q738 E893 M894 E897	V48 K52 Q65 M66 I69 Q70 E225 M226 E229
BS02	DHT	A	L704 N705 Q711 M745 M749 F764 T877	L36 N37 Q43 M77 M81 F96 T209

External links

PDB	RCSB:1t79, PDBe:1t79, PDBj:1t79
PDBsum	1t79
PubMed	15328534
UniProt	O97775\|ANDR_PANTR Androgen receptor (Gene Name=AR)

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