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Structure of PDB 1h9d Chain A

Receptor sequence >1h9dA (length=125) Species: 9606 (Homo sapiens) [Search protein sequence] VLADHPGELVRTDSPNFLCSVLPTHWRCNKTLPIAFKVVALGDVPDGTLV TVMAGNDENYSAELRNATAAMKNQVARFNDLRFVGRSGRGKSFTLTITVF TNPPQVATYHRAIKITVDGPREPRR

3D structure PDB 1h9d The Leukemia-Associated Aml1 (Runx1)-Cbfbeta Complex Functions as a DNA-Induced Molecular Clamp Chain A Resolution 2.6 Å 3D structure [Spin on] [Spin off] [Reset orientation] [High quality] [Low quality] [White background] [Black background] [Download] [Download structure with residue number starting from 1]

Enzymatic activity Enzyme Commision number ?

Interaction with ligand Site # Ligand Ligand chain Binding residues on receptor (original residue number in PDB) Binding residues on receptor (residue number reindexed from 1) Binding affinity BS01 dna A R80 R135 R142 R174 R177 R27 R82 R89 R121 R124 PDBbind-CN: Kd=10pM BS02 dna A R142 G143 K167 T169 V170 D171 R89 G90 K114 T116 V117 D118 PDBbind-CN: Kd=10pM

Gene Ontology Molecular Function GO:0003677 DNA binding GO:0003700 DNA-binding transcription factor activity GO:0005524 ATP binding

	Biological Process
GO:0006355	regulation of DNA-templated transcription

	Cellular Component
GO:0005634	nucleus

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