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Structure of PDB 1bxo Chain A

Receptor sequence >1bxoA (length=323) Species: 5079 (Penicillium janthinellum) [Search protein sequence] AASGVATNTPTANDEEYITPVTIGGTTLNLNFDTGSADLWVFSTELPASQ QSGHSVYNPSATGKELSGYTWSISYGDGSSASGNVFTDSVTVGGVTAHGQ AVQAAQQISAQFQQDTNNDGLLGLAFSSINTVQPQSQTTFFDTVKSSLAQ PLFAVALKHQQPGVYDFGFIDSSKYTGSLTYTGVDNSQGFWSFNVDSYTA GSQSGDGFSGIADTGTTLLLLDDSVVSQYYSQVSGAQQDSNAGGYVFDCS TNLPDFSVSISGYTATVPGSLINYGPSGDGSTCLGGIQSNSGIGFSIFGD IFLKSQYVVFDSDGPQLGFAPQA

3D structure PDB 1bxo Lowering the entropic barrier for binding conformationally flexible inhibitors to enzymes. Chain A Resolution 0.95 Å 3D structure Catalytic site residues are labeled in the structure [Spin on] [Spin off] [Reset orientation] [High quality] [Low quality] [White background] [Black background] [Download] [Download structure with residue number starting from 1]

Enzymatic activity Catalytic site (original residue number in PDB) D33 S36 D38 W40 Y75 D213 T216 Catalytic site (residue number reindexed from 1) D33 S36 D38 W40 Y75 D213 T216 Enzyme Commision number 3.4.23.20: penicillopepsin.

Interaction with ligand Site # Ligand Ligand chain Binding residues on receptor (original residue number in PDB) Binding residues on receptor (residue number reindexed from 1) Binding affinity BS01 MAN A V5 T7 V5 T7 BS02 PP7 A E15 D33 G35 Y75 G76 D77 D213 G215 T216 T217 I297 E15 D33 G35 Y75 G76 D77 D213 G215 T216 T217 I297 MOAD: Ki=0.1nM PDBbind-CN: -logKd/Ki=10.00,Ki=0.10nM

Gene Ontology Molecular Function GO:0004190 aspartic-type endopeptidase activity

	Biological Process
GO:0006508	proteolysis

	Cellular Component
GO:0005576	extracellular region

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