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BioLiP

Structure of PDB 4zcu Chain C Binding Site BS03

Receptor Information
>4zcu Chain C (length=150) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TRYETLFQALDRNGDGVVDIGELQEGLRNLGIPLGQDAEEKIFTTGDVNK
DGKLDFEEFMKYLKDHEKKMKLAFKSLDKNNDGKIEASEIVQSLQTLGLT
ISEQQAELILQSIDVDTVDWNEWRDYFLFNPVTDIEEIIRFWKHSTGIDI
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain4zcu Chain C Residue 1003 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB4zcu Calcium-induced conformational changes in the regulatory domain of the human mitochondrial ATP-Mg/Pi carrier.
Resolution2.1 Å
Binding residue
(original residue number in PDB)		D99 N101 D103 K105 E107 E110
Binding residue
(residue number reindexed from 1)		D78 N80 D82 K84 E86 E89
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding

View graph for
Molecular Function
External links
PDB RCSB:4zcu, PDBe:4zcu, PDBj:4zcu
PDBsum4zcu
PubMed26164100
UniProtQ6NUK1|SCMC1_HUMAN Mitochondrial adenyl nucleotide antiporter SLC25A24 (Gene Name=SLC25A24)

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