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Structure of PDB 4or0 Chain B Binding Site BS03

Receptor Information >4or0 Chain B (length=582) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] THKSEIAHRFKDLGEEHFKGLVLIAFSQYLQQCPFDEHVKLVNELTEFAK TCVADESHAGCEKSLHTLFGDELCKVASLRETYGDMADCCEKQEPERNEC FLSHKDDSPDLPKLKPDPNTLCDEFKADEKKFWGKYLYEIARRHPYFYAP ELLYYANKYNGVFQECCQAEDKGACLLPKIETMREKVLTSSARQRLRCAS IQKFGERALKAWSVARLSQKFPKAEFVEVTKLVTDLTKVHKECCHGDLLE CADDRADLAKYICDNQDTISSKLKECCDKPLLEKSHCIAEVEKDAIPENL PPLTADFAEDKDVCKNYQEAKDAFLGSFLYEYSRRHPEYAVSVLLRLAKE YEATLEECCAKDDPHACYSTVFDKLKHLVDEPQNLIKQNCDQFEKLGEYG FQNALIVRYTRKVPQVSTPTLVEVSRSLGKVGTRCCTKPESERMPCTEDY LSLILNRLCVLHEKTPVSEKVTKCCTESLVNRRPCFSALTPDETYVPKAF DEKLFTFHADICTLPDTEKQIKKQTALVELLKHKPKATEEQLKTVMENFV AFVDKCCAADDKEACFAVEGPKLVVSTQTALA

Ligand information Ligand ID NPS InChI InChI=1S/C14H14O3/c1-9(14(15)16)10-3-4-12-8-13(17-2)6-5-11(12)7-10/h3-9H,1-2H3,(H,15,16)/t9-/m0/s1 InChIKey CMWTZPSULFXXJA-VIFPVBQESA-N SMILES Software SMILES OpenEye OEToolkits 1.5.0 CC(c1ccc2cc(ccc2c1)OC)C(=O)O CACTVS 3.341 COc1ccc2cc(ccc2c1)[C@H](C)C(O)=O ACDLabs 10.04 O=C(O)C(c1ccc2c(c1)ccc(OC)c2)C OpenEye OEToolkits 1.5.0 C[C@@H](c1ccc2cc(ccc2c1)OC)C(=O)O CACTVS 3.341 COc1ccc2cc(ccc2c1)[CH](C)C(O)=O Formula C14 H14 O3 Name (2S)-2-(6-methoxynaphthalen-2-yl)propanoic acid; NAPROXEN ChEMBL CHEMBL154 DrugBank DB00788 ZINC ZINC000000105216 PDB chain 4or0 Chain B Residue 603 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 4or0 Structural studies of bovine, equine, and leporine serum albumin complexes with naproxen. Resolution 2.58 Å Binding residue (original residue number in PDB) R194 L197 S201 W213 R217 L346 Binding residue (residue number reindexed from 1) R193 L196 S200 W212 R216 L345 Annotation score 1

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0003677 DNA binding GO:0005504 fatty acid binding GO:0005515 protein binding GO:0008289 lipid binding GO:0015643 toxic substance binding GO:0019825 oxygen binding GO:0030170 pyridoxal phosphate binding GO:0046872 metal ion binding GO:1903981 enterobactin binding

	Biological Process
GO:0009267	cellular response to starvation
GO:0051902	negative regulation of mitochondrial depolarization
GO:0072732	cellular response to calcium ion starvation

	Cellular Component
GO:0005576	extracellular region
GO:0005615	extracellular space
GO:0005737	cytoplasm
GO:0032991	protein-containing complex

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