BioLiP

Structure of PDB 1n2t Chain B Binding Site BS03

Receptor Information

>1n2t Chain B (length=385) Species: 1147 (Synechocystis sp. PCC 6714) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

TPDRHQFPGLANKTYFNFGGQGILPTVALEAITAMYGYLQENGPFSIAAN
QHIQQLIAQLRQALAETFNVDPNTITITDNVTTGCDIVLWGLDWHQGDEI
LLTDCEHPGIIAIVQAIAARFGITYRFFPVAATLNQGDAAAVLANHLGPK
TRLVILSHLLWNTGQVLPLAEIMAVCRRHQGNYPVRVLVDGAQSAGSLPL
DFSRLEVDYYAFTGHAWFAGPAGVGGLYIHGDCLGEINPTYVGWRSITYG
AKGEPTGWAEGGKRFEVATSAYPQYAGLLAALQLHQRQGTAEERYQAICQ
RSEFLWRGLNQLPHVHCLATSAPQAGLVSFTVDSPLGHRAIVQKLEEQRI
YLRTIADPDCIRACCHYITDEEEINHLLARLADFG

Ligand information

Ligand ID

GLY

InChI

InChI=1S/C2H5NO2/c3-1-2(4)5/h1,3H2,(H,4,5)

InChIKey

DHMQDGOQFOQNFH-UHFFFAOYSA-N

SMILES

Software	SMILES
OpenEye OEToolkits 1.5.0	C(C(=O)O)N
CACTVS 3.341	NCC(O)=O
ACDLabs 10.04	O=C(O)CN

Formula

C2 H5 N O2

Name

GLYCINE

PDB chain

1n2t Chain B Residue 2002 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	1n2t Snapshots of the Cystine Lyase "C-DES" during Catalysis: Studies in Solution and in the Crystalline State
Resolution	2.0 Å
Binding residue (original residue number in PDB)	G26 R360 R369
Binding residue (residue number reindexed from 1)	G19 R353 R362
Annotation score	4

Enzymatic activity

Catalytic site (original residue number in PDB)	H114 D197 A199 Q200 A223 R360
Catalytic site (residue number reindexed from 1)	H107 D190 A192 Q193 A216 R353
Enzyme Commision number	4.4.1.-

Gene Ontology

	Molecular Function
GO:0016829	lyase activity

View graph for
Molecular Function

PDB	RCSB:1n2t, PDBe:1n2t, PDBj:1n2t
PDBsum	1n2t
PubMed	12386155
UniProt	Q9ZHG9