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BioLiP

Structure of PDB 9asp Chain A Binding Site BS03

Receptor Information
>9asp Chain A (length=914) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VWIRCTHSENYYSSDPMDQVGDSTVVGTSRLRDLYDKFEEELGSRQEKAK
AARPPWEPVFDVIAEIKRKKAHPDRLHDELWYNDPGQMNDGPLCKCSAKA
RRTGIRHSIYPGEEAIKPCRPMTNNAGRLFHYRITVSPPTNFLTDRPTVI
EYDDHEYIFEGFSMFAHAPLTNIPLCKVIRFNIDYTIHFIEEMMPENFCV
KGLELFSLFLFRDILELYDWNLKGPLFEDSPPCCPRFHFMPRFVRFLPDG
GKEVLSMHQILLYLLRCSKALVPEEEIANMLQWEELEWQKYAEECKGMIV
TNPGTKPSSVRIDQLDREQFNPDVITFPIIVHFGIRPAQLSYAGDPQYQK
LWKSYVKLRHLLANSPKVKQTDKQKLAQREEALQKIRQKNTMRREVTVEL
SSQGFWKTGIRSDVCQHAMMLPVLTHHIRYHQCLMHLDKLIGYTFQDRCL
LQLAMTHPSHHLNFGMNPDHARNSLSNCGIRQPKYGDRKVHHMHMRKKGI
NTLINIMSRLGQDDPTPSRINHNERLEFLGDAVVEFLTSVHLYYLFPSLE
EGGLATYRTAIVQNQHLAMLAKKLELDRFMLYAHGPDLCRESDLRHAMAN
CFEALIGAVYLEGSLEEAKQLFGRLLFNDPDLREVWLNYPLHPLQLQEPN
TDRQLIETSPVLQKLTEFEEAIGVIFTHVRLLARAFTLRTVGFNHLTLGH
NQRMEFLGDSIMQLVATEYLFIHFPDHHEGHLTLLRSSLVNNRTQAKVAE
ELGMQEYAITNDKTKRPVALRTKTLADLLESFIAALYIDKDLEYVHTFMN
VCFFPRLKEFILNQDWNDPKSQLQQCCLTLRTEGKEPDIPLYKTLQTVGP
SHARTYTVAVYFKGERIGCGKGPSIQQAEMGAAMDALEKYNFPQMAHQKR
FIERKYRQELKEMR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain9asp Chain A Residue 1402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB9asp RNAi_protein_a1
Resolution3.2 Å
Binding residue
(original residue number in PDB)		C538 H549 H1026
Binding residue
(residue number reindexed from 1)		C96 H107 H584
Annotation score4
External links
PDB RCSB:9asp, PDBe:9asp, PDBj:9asp
PDBsum9asp
PubMed
UniProtQ9NRR4|RNC_HUMAN Ribonuclease 3 (Gene Name=DROSHA)

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