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Structure of PDB 6utv Chain FFF Binding Site BS02

Receptor Information >6utv Chain FFF (length=277) Species: 83333 (Escherichia coli K-12) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] RVLDATQLYLGEIGYSPLLTAEEEVYFARRALRGDVASRRRMIESNLRLV VKIARRYGNRGLALLDLIEEGNLGLIRAVEKFDPERGFRFSTYATWWIRQ TIERAIMNQTRTIRLPIHIVKELNVYLRTARELSHKLDHEPSAEEIAEQL DKPVDDVSRMLRLNERITSVDTPLGGDSEKALLDILADEKENGPEDTTQD DDMKQSIVKWLFELNAKQREVLARRFGLLGYEAATLEDVGREIGLTRERV RQIQVEGLRRLREILQTQGLNIEALFL

Ligand information >6utv Chain 222 (length=35) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] tccgcgtcagactcgtaattatagcatacgtgagg

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 6utv Structural Insights into Transcription Initiation from De Novo RNA Synthesis to Transitioning into Elongation. Resolution 3.45 Å Binding residue (original residue number in PDB) R112 E155 I158 M159 V172 K173 N176 R180 R183 R218 L226 E231 L234 Binding residue (residue number reindexed from 1) R60 E103 I106 M107 V120 K121 N124 R128 R131 R166 L174 E179 L182

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0001000 bacterial-type RNA polymerase core enzyme binding GO:0003677 DNA binding GO:0003700 DNA-binding transcription factor activity GO:0005515 protein binding GO:0016987 sigma factor activity

	Biological Process
GO:0006351	DNA-templated transcription
GO:0006352	DNA-templated transcription initiation
GO:0006355	regulation of DNA-templated transcription
GO:0006950	response to stress
GO:0010468	regulation of gene expression
GO:0045892	negative regulation of DNA-templated transcription
GO:2000142	regulation of DNA-templated transcription initiation

	Cellular Component
GO:0000345	cytosolic DNA-directed RNA polymerase complex
GO:0005737	cytoplasm
GO:1903865	sigma factor antagonist complex

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