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Structure of PDB 8vuw Chain C Binding Site BS02

Receptor Information >8vuw Chain C (length=311) Species: 556 (Dickeya chrysanthemi) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] PVDVSVSIFINKIYGVNTLEQTYKVDGYIVAQWTGKPRKTPGDKPLIVEN TQIERWINNGLWVPALEFINVVGSPDTGNKRLMLFPDGRVIYNARFLGSF SNDMDFRLFPFDRQQFVLELEPFSYNNQQLRFSDIQVYTENIDNEEIDEW WIRGKASTHISDIRYDHLSSVQPNQNEFSRITVRIDAVRNPSYYLWSFIL PLGLIIAASWSVFWLESFSERLQTSFTLMLTVVAYAFYTSNILGRLPYTT YIDQMIIAGYGSIFAAILLIIFAHHRQANGVEDDLLIQRSRLAFPLGFLA IGCVLVIRFFT

Ligand information Ligand ID DHL InChI InChI=1S/C2H7NS/c3-1-2-4/h4H,1-3H2 InChIKey UFULAYFCSOUIOV-UHFFFAOYSA-N SMILES Software SMILES ACDLabs 10.04 SCCN OpenEye OEToolkits 1.5.0 C(CS)N CACTVS 3.341 NCCS Formula C2 H7 N S Name 2-AMINO-ETHANETHIOL; 2,3-DESHYDROLANTHIONINE ChEMBL CHEMBL602 DrugBank DB00847 ZINC ZINC000008034121 PDB chain 8vuw Chain C Residue 402 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 8vuw Open-channel structure of a pentameric ligand-gated ion channel reveals a mechanism of leaflet-specific phospholipid modulation. Resolution 3.19 Å Binding residue (original residue number in PDB) E77 E131 Y175 H177 F188 Binding residue (residue number reindexed from 1) E67 E121 Y165 H167 F178 Annotation score 1

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0004888 transmembrane signaling receptor activity GO:0005216 monoatomic ion channel activity GO:0005230 extracellular ligand-gated monoatomic ion channel activity

	Biological Process
GO:0006811	monoatomic ion transport
GO:0034220	monoatomic ion transmembrane transport

	Cellular Component
GO:0016020	membrane

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