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BioLiP

Structure of PDB 1kc6 Chain C Binding Site BS02

Receptor Information
>1kc6 Chain C (length=233) Species: 727 (Haemophilus influenzae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SFIKPIYQDINSILIGQKVKAGEPFEKLVYKFLKENLSDLTFKQYEYLND
LFHEARYKLFNSPTLLFLLSRGKAATENWSIFEEKQNDTADILLVKQFYE
LLDVKTRNISKSAQAPNIISAYKLAQTCAKMIDNKEFDLFDINYLEVDWE
LNGEDLVCVSTSFAELFKSEPSELYINWAAAMQIQFHVRDLDQGFNGTRE
EWAKSYLKHFVTQAEQRAISMIDKFVKPFKKYI
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1kc6 Sequence selectivity and degeneracy of a restriction endonuclease mediated by DNA intercalation.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		Q109 N110 D127 T130 R131 N132 K135 S136 A137 Q138 N141 S144 Y146 K147 A205 M206 Q207
Binding residue
(residue number reindexed from 1)		Q86 N87 D103 T106 R107 N108 K111 S112 A113 Q114 N117 S120 Y122 K123 A181 M182 Q183
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function
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Biological Process
External links
PDB RCSB:1kc6, PDBe:1kc6, PDBj:1kc6
PDBsum1kc6
PubMed11742344
UniProtP17743|T2C2_HAEIF Type II restriction enzyme HincII (Gene Name=hincIIR)

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