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BioLiP

Structure of PDB 8vpi Chain B Binding Site BS02

Receptor Information
>8vpi Chain B (length=551) Species: 1496 (Clostridioides difficile) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SGIYYTPKIIVDYIVKKTLKNHDIIKNPYPRILDISCGCGNFLLEVYDIL
YDLFEENIYELKKKYDENYWTVDNIHRHILNYCIYGADIDEKAISILKDS
LTNKKVVNDLDESDIKINLFCCDSLKKKWRYKFDYIVGNPPYIGHKKLEK
KYKKFLLEKYSEVYKDKADLYFCFYKKIIDILKQGGIGSVITPRYFLESL
SGKDLREYIKSNVNVQEIVDFLGANIFKNIGVSSCILTFDKKKTKETYID
VFKIKNEDICINKFETLEELLKSSKFEHFNINQRLLSDEWILVNKDDETF
YNKIQEKCKYSLEDIAISFQGIITGCDKAFILSKDDVKLNLVDDKFLKCW
IKSKNINKYIVDKSEYRLIYSNDIDNENTNKRILDEIIGLYKTKLENRRE
CKSGIRKWYELQWGREKLFFERKKIMYPYKSNENRFAIDYDNNFSSADVY
SFFIKEEYLDKFSYEYLVGILNSSVYDKYFKITAKKMSKNIYDYYPNKVM
KIRIFRDNNYEEIENLSKQIISILLNKSIDKGKVEKLQIKMDNLIMDSLG
I
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8vpi Quinoline-based compounds can inhibit diverse enzymes that act on DNA
Resolution2.89 Å
Binding residue
(original residue number in PDB)		H171 K172 K176 K179 D192 K193 I349 G351 D353 K378 K380 R425 Q438 W439 Y455 K456
Binding residue
(residue number reindexed from 1)		H145 K146 K150 K153 D166 K167 I323 G325 D327 K352 K354 R399 Q412 W413 Y429 K430
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