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●I-TASSER ●I-TASSER-MTD ●C-I-TASSER ●CR-I-TASSER ●QUARK ●C-QUARK ●LOMETS ●MUSTER ●CEthreader ●SEGMER ●DeepFold ●DeepFoldRNA ●FoldDesign ●COFACTOR ●COACH ●MetaGO ●TripletGO ●IonCom ●FG-MD ●ModRefiner ●REMO ●DEMO ●DEMO-EM ●SPRING ●COTH ●Threpp ●PEPPI ●BSpred ●ANGLOR ●EDock ●BSP-SLIM ●SAXSTER ●FUpred ●ThreaDom ●ThreaDomEx ●EvoDesign ●BindProf ●BindProfX ●SSIPe ●GPCR-I-TASSER ●MAGELLAN ●ResQ ●STRUM ●DAMpred

●TM-score ●TM-align ●US-align ●MM-align ●RNA-align ●NW-align ●LS-align ●EDTSurf ●MVP ●MVP-Fit ●SPICKER ●HAAD ●PSSpred ●3DRobot ●MR-REX ●I-TASSER-MR ●SVMSEQ ●NeBcon ●ResPRE ●TripletRes ●DeepPotential ●WDL-RF ●ATPbind ●DockRMSD ●DeepMSA ●FASPR ●EM-Refiner ●GPU-I-TASSER

●BioLiP ●E. coli ●GLASS ●GPCR-HGmod ●GPCR-RD ●GPCR-EXP ●Tara-3D ●TM-fold ●DECOYS ●POTENTIAL ●RW/RWplus ●EvoEF ●HPSF ●THE-DB ●ADDRESS ●Alpaca-Antibody ●CASP7 ●CASP8 ●CASP9 ●CASP10 ●CASP11 ●CASP12 ●CASP13 ●CASP14

Structure of PDB 3avx Chain A Binding Site BS02

Receptor Information >3avx Chain A (length=1203) Species: 39803,83334 [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] AEITASLVKELRERTGAGMMDCKKALTEANGDIELAIENMRKSGAIKAAK KAGNVAADGVIKTKIDGNYGIILEVNCQTDFVAKDAGFQAFADKVLDAAV AGKITDVEVLKAQFEEERVALVAKIGENINIRRVAALEGDVLGSYQHGAR IGVLVAAKGADEELVKHIAMHVAASKPEFIKPEDVSAEVVEKEYQVQLDI AMQSGKPKEIAEKMVEGRMKKFTGEVSLTGQPFVMEPSKTVGQLLKEHNA EVTGFIRFEVGEGIEKVETDFAAEVAAMSKQSHMSFERTKPHVNVGTIGH VDHGKTTLTAAITTVLAKTYGGNTSHVEYDTPTRHYAHVDCPGHADYVKN MITGAAQMDGAILVVAATDGPMPQTREHILLGRQVGVPYIIVFLNKCDMV DDEELLELVEMEVRELLSQYDFPGDDTPIVRGSALKALEGDAEWEAKILE LAGFLDSYIPEPERAIDKPFLLPIEDVFSISGRGTVVTGRVERGIIKVGE EVEIVGIKETQKSTCTGVEMFRKLLDEGRAGENVGVLLRGIKREEIERGQ VLAKPGTIKPHTKFESEVYILSKDEGGRHTPFFKGYRPQFYFRTTDVTGT IELPEGVEMVMPGDNIKMVVTLIHPIAMDDGLRFAIREGGRTVGAGVVAK VLSGASSRNSLSAQLRRAANTRIEVEGNLALSIANDLLLAYGQSPFNSEA ECISFSPRFDGTPDDFRINYLKAEIMSKYDDFSLGIDTEAVAWEKFLAAE AECALTNARLYRPDYSEDFNFSLGESCIHMARRKIAKLIGDVPSVEGMLR HCRFSGGATTTNNRSYGHPSFKFALPQACTPRALKYVLALRASTHFDIRI SDISPFNKAVTVPKNSKTDRCIAIEPGWNMFFQLGIGGILRDRLRCWGID LNDQTINQRRAHEGSVTNNLATVDLSAASDSISLALCELLLPPGWFEVLM DLRSPKGRLPDGSVVTYEKISSMGNGYTFELESLIFASLARSVCEILDLD SSEVTVYGDDIILPSCAVPALREVFKYVGFTTNTKKTFSEGPFRESCGKH YYSGVDVTPFYIRHRIVSPADLILVLNNLYRWATIDGVWDPRAHSVYLKY RKLLPKQLQRNTIPDGYGDGALVGSVLINPFAKNRGWIRYVPVITDHTRD RERAELGSYLYDLFSRCLSESNAIDQLICRSNPTKISRSTGKFDIQYIAC SSR

Ligand information >3avx Chain T (length=13) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] aacgauggaccca .............

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 3avx Molecular basis for RNA polymerization by Q beta replicase Resolution 2.406 Å Binding residue (original residue number in PDB) R573 T620 R662 R847 S849 G850 G851 A852 N857 R858 P907 I916 M924 R935 N946 G1018 Y1051 G1160 Y1161 N1243 Q1257 Binding residue (residue number reindexed from 1) R548 T595 R637 R803 S805 G806 G807 A808 N813 R814 P863 I872 M880 R891 N902 G974 Y1007 G1116 Y1117 N1182 Q1196

Enzymatic activity Catalytic site (original residue number in PDB) D306 K309 T310 H369 Catalytic site (residue number reindexed from 1) D302 K305 T306 H344 Enzyme Commision number ? 2.7.7.48: RNA-directed RNA polymerase.

Gene Ontology Molecular Function GO:0000166 nucleotide binding GO:0003723 RNA binding GO:0003746 translation elongation factor activity GO:0003924 GTPase activity GO:0003968 RNA-dependent RNA polymerase activity GO:0005515 protein binding GO:0005525 GTP binding GO:0034062 5'-3' RNA polymerase activity GO:0046872 metal ion binding GO:0097216 guanosine tetraphosphate binding

	Biological Process
GO:0001172	RNA-templated transcription
GO:0006412	translation
GO:0006414	translational elongation
GO:0019079	viral genome replication
GO:0039694	viral RNA genome replication
GO:0046677	response to antibiotic

	Cellular Component
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005886	plasma membrane

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