BioLiP

Structure of PDB 1z19 Chain A Binding Site BS02

Receptor Information

>1z19 Chain A (length=273) Species: 10710 (Lambdavirus lambda) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MTLHSWLDRYEKILASRGIKQKTLINYMSKIKAIRRGLPDAPLEDITTKE
IAAMLNGYIDEGKAASAKLIRSTLSDAFREAIAEGHITTNHVAATRAAKS
KVRRSRLTADEYLKIYQAAESSPCWLRLAMELAVVTGQRVGDLCEMKWSD
IVDGYLYVEQSKTGVKIAIPTALHIDALGISMKETLDKCKEILGGETIIA
STRREPLSSGTVSRYFMRARKASGLSFEGDPPTFHELRSLSARLYEKQIS
DKFAQHLLGHKSDTMEWDKIEIK

Ligand information

>1z19 Chain E (length=33) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

taatgccaacttagtataaaaaagctgaacgag

Receptor-Ligand Complex Structure

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Structure summary

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PDB	1z19 A structural basis for allosteric control of DNA recombination by lambda integrase.
Resolution	2.8 Å
Binding residue (original residue number in PDB)	K136 A138 S139 V175 R176 R177 W198 R212 K235 S274 T275 L280 S281 T284 Y288 H308 R311 H333 K334 M338
Binding residue (residue number reindexed from 1)	K63 A65 S66 V102 R103 R104 W125 R139 K162 S201 T202 L207 S208 T211 Y215 H235 R238 H260 K261 M265

Enzymatic activity

Enzyme Commision number

2.7.7.-
3.1.-.-

Gene Ontology

	Molecular Function
GO:0003677	DNA binding

	Biological Process
GO:0006310	DNA recombination
GO:0015074	DNA integration

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Molecular Function

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Biological Process

PDB	RCSB:1z19, PDBe:1z19, PDBj:1z19
PDBsum	1z19
PubMed	15973401
UniProt	P03700\|VINT_LAMBD Integrase (Gene Name=int)