BioLiP

Structure of PDB 1sa3 Chain A Binding Site BS02

Receptor Information

>1sa3 Chain A (length=262) Species: 479 (Moraxella sp.) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MRTELLSKLYDDFGIDQLPHTQHGVTSDRLGKLYEKYILDIFKDIESLKK
YNTNAFPQEKDISSKLLKALNLDLDNIIDVSSSDTDLGRTIAGGSPKTDA
TIRFTFHNQSSRLVPLNIKHSSKKKVSIAEYDVETICTGVGISDGELKEL
IRKHQNDQSAKLFTPVQKQRLTELLEPYRERFIRWCVTLRAEKSEGNILH
PDLLIRFQVIDREYVDVTIKNIDDYVSDRIAEGSKARKPGFGTGLNWTYA
SGSKAKKMQFKG

Ligand information

>1sa3 Chain D (length=9) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

ccccggggg

Receptor-Ligand Complex Structure

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Structure summary

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PDB	1sa3 An Asymmetric Complex of Restriction Endonuclease MspI on Its Palindromic DNA Recognition Site.
Resolution	1.95 Å
Binding residue (original residue number in PDB)	S159 A160 K161 T248 Y249 S251
Binding residue (residue number reindexed from 1)	S159 A160 K161 T248 Y249 S251

Enzymatic activity

Enzyme Commision number

3.1.21.4: type II site-specific deoxyribonuclease.

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0004519	endonuclease activity
GO:0009036	type II site-specific deoxyribonuclease activity

	Biological Process
GO:0009307	DNA restriction-modification system

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Biological Process

PDB	RCSB:1sa3, PDBe:1sa3, PDBj:1sa3
PDBsum	1sa3
PubMed	15341737
UniProt	P11405\|T2M1_MORSP Type II restriction enzyme MspI (Gene Name=mspIR)