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Structure of PDB 8wi7 Chain u Binding Site BS01

Receptor Information >8wi7 Chain u (length=85) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] ANIKSQIKRIRTNERRRLRNQSVKSSLRTAIRGFREAVDAGDKDKASELL HATSRKLDKAASKGVIHPNQAANKKSALALALNKL

Ligand information >8wi7 Chain a (length=1515) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] uggagaguuugauccuggcucaggacgaacgcuggcggcgugcuuaacac augcaagucgaacggaaaggcccuuucggggguacucgaguggcgaacgg gugaguaacacgugggugaucugcccugcacuuugggauaagccugggaa acugggucuaauaccgaauacacccugcuggucgcauggccugguagggg aaagcuuuugcggugugggaugggcccgcggccuaucagcuuguuggugg ggugauggccuaccaaggcgacgacggguagccggccugagagggugacc ggccacacugggacugagauacggcccagacuccuacgggaggcagcagu ggggaauauugcacaaugggcgcaagccugaugcagcgacgccgcgugag ggaugacggccuucggguuguaaaccucuuucagcacagacgaagcgcaa gugacgguaugugcagaagaaggaccggccaacuacgugccagcagccgc gguaauacguaggguccgagcguuguccggaauuacugggcguaaagagc ucguaggugguuugucgcguuguucgugaaaacucacagcuuaacugugg gcgugcgggcgauacgggcagacuagaguacugcaggggagacuggaauu ccugguguagcgguggaaugcgcagauaucaggaggaacaccgguggcga aggcgggucucugggcaguaacugacgcugaggagcgaaagcguggggag cgaacaggauuagauacccugguaguccacgccguaaacgguggguacua gguguggguuuccuuccuugggauccgugccguagcuaacgcauuaagua ccccgccuggggaguacggccgcaaggcuaaaacucaaaggaauugacgg gggcccgcacaagcggcggagcauguggauuaauucgaugcaacgcgaag aaccuuaccuggguuugacaugcacaggacgccggcagagaugucgguuc ccuuguggccugugugcagguggugcauggcugucgucagcucgugucgu gagauguuggguuaagucccgcaacgagcgcaacccuugucucauguugc cagcacguuaugguggggacucgugagagacugccggggucaacucggag gaagguggggaugacgucaagucaucaugccccuuauguccagggcuuca cacaugcuacaauggccgguacaaagggcugcgaugccgugagguggagc gaauccuuucaaagccggucucaguucggaucggggucugcaacucgacc ccgugaagucggagucgcuaguaaucgcagaucagcaacgcugcggugaa uacguucccgggccuuguacacaccgcccgucacgucaugaaagucggua acacccgaagccgguggccuaacccuuguggagggagccgucgaaggugg gaucggcgauugggacgaagucguaacaagguagccguaccggaaggugc ggcuggaucaccucc ....<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<<< .<<<..<<<..<<.<..<<<<<<<....>>>>>.>>>..>>>>>...... <<........<<<<<<<..<<...<<<<<<<<<<<<.....<<<<<<... .>>>>>>......>>>>.....<<<<<<<<<<<<..>>>>>.>>>>>>>. ...<<....>>>>>>>>>>..>>>>>>>>>.<<<....<<<..<<<<<<< <.......>>>>>>>>>>>......>>>..<<<<<<<<....>>>>...> >>>.>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>>> >.........<<<....<<<<....>>>>..>>>..>>.>>>>>>..<<< <......<<<<....>>>>.....>>>>...<.<<<<<......<<.... >>.......>>>>>....>..<<<<<(((...<<<<<.....<<.)))>> .......>>>>>>>>>>..>>>>>>>>>..........<<<((.....<< <<...<<<.<<<<<<<.<<<<<<<<<<.....<<<<<<<.....>>>>>> >...>>>>>>>..>>>>>>>>>>...<<<<<<<<...<<<<<<<....<< <<<<<<<..<<<......>>>.....>>>>>>>>>...........<<.. ..>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....<<<<<<...< <...<<<<.<.....>.>>>>...>>>>>>>>..........<<<<<<.. <<<<<<<<<<<<.......>>>>>>>>>>>>...<<..))>>.....>>> >>>.>>>.<<<......<<<<....>>>>....>>>..)))).]<<<<<. <<<<<<<.<<.<<<<<<..<<<<<<<<<<......<<........>>... .......<<<<<<<......<<<<<<<...<<<<<<<....>>>>>>>.< <.....>>.>>>>>>>.<<<.<<<..<<<<<<.......<<<<<<<<<.. ..>>>..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<....< <..<<<......>>>>>.....>>>>>>.....<<<<<.....>>>>>.. ......>>>>.........>>>...>>>>>>>>>...>>>>>>>...>>. >>>>>>>>.....<<<<<<<.....<<<..<<..<<<<....>>>>..>> ....>>>......>>>>>>>......<....<<<<<<<........>>>> >>>....>.....>>>>>>....<<<<<<<..........>>>>>>>... ...>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<<. .<<<<....<.<<<<..<<<..<<.....>>.>>>.>>>>.>...>>>>. .>>>>>>..>>>.>>>>..>.>>...>.....<<<<<<<<<....>>>>> >>>>...........

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 8wi7 Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH. Resolution 3.5 Å Binding residue (original residue number in PDB) A2 N3 I4 K5 Q7 K9 R10 R12 R16 R17 R18 R20 N21 S26 S27 R29 T30 R33 R56 D59 K60 S63 K64 N70 A73 N74 K76 S77 N84 Binding residue (residue number reindexed from 1) A1 N2 I3 K4 Q6 K8 R9 R11 R15 R16 R17 R19 N20 S25 S26 R28 T29 R32 R55 D58 K59 S62 K63 N69 A72 N73 K75 S76 N83

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0003723 RNA binding GO:0003735 structural constituent of ribosome GO:0019843 rRNA binding GO:0070181 small ribosomal subunit rRNA binding

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005829	cytosol
GO:0005840	ribosome
GO:0015935	small ribosomal subunit
GO:1990904	ribonucleoprotein complex

View graph for Molecular Function

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View graph for Cellular Component