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Structure of PDB 8wib Chain m Binding Site BS01

Receptor Information >8wib Chain m (length=122) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] PTIQQLVRKGRRDKIAKVKTAALKGSPQRRGVCTRVYTTTPKKPNSALRK VARVKLTSQVEVTAYIPGEGHNLQEHSMVLVRGGRVKDLPGVRYKIIRGS LDTQGVKNRKQARSRYGAKKEK

Ligand information >8wib Chain a (length=1515) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] uuggagaguuugauccuggcucaggacgaacgcuggcggcgugcuuaaca caugcaagucgaacggaaaggcccuuucggggguacucgaguggcgaacg ggugaguaacacgugggugaucugcccugcacuuugggauaagccuggga aacugggucuaauaccgaauacacccugcuggucgcauggccugguaggg gaaagcuuuugcggugugggaugggcccgcggccuaucagcuuguuggug gggugauggccuaccaaggcgacgacggguagccggccugagagggugac cggccacacugggacugagauacggcccagacuccuacgggaggcagcag uggggaauauugcacaaugggcgcaagccugaugcagcgacgccgcguga gggaugacggccuucggguuguaaaccucuuucagcacagacgaagcgca agugacgguaugugcagaagaaggaccggccaacuacgugccagcagccg cgguaauacguaggguccgagcguuguccggaauuacugggcguaaagag cucguaggugguuugucgcguuguucgugaaaacucacagcuuaacugug ggcgugcgggcgauacgggcagacuagaguacugcaggggagacuggaau uccugguguagcgguggaaugcgcagauaucaggaggaacaccgguggcg aaggcgggucucugggcaguaacugacgcugaggagcgaaagcgugggga gcgaacaggauuagauacccugguaguccacgccguaaacgguggguacu agguguggguuuccuuccuugggauccgugccguagcuaacgcauuaagu accccgccuggggaguacggccgcaaggcuaaaacucaaaggaauugacg ggggcccgcacaagcggcggagcauguggauuaauucgaugcaacgcgaa gaaccuuaccuggguuugacaugcacaggacgccggcagagaugucgguu cccuuguggccugugugcagguggugcauggcugucgucagcucgugucg ugagauguuggguuaagucccgcaacgagcgcaacccuugucucauguug ccagcacguuaugguggggacucgugagagacugccggggucaacucgga ggaagguggggaugacgucaagucaucaugccccuuauguccagggcuuc acacaugcuacaauggccgguacaaagggcugcgaugccgugagguggag cgaauccuuucaaagccggucucaguucggaucggggucugcaacucgac cccgugaagucggagucgcuaguaaucgcagaucagcaacgcugcgguga auacguucccgggccuuguacacaccgcccgucacgucaugaaagucggu aacacccgaagccgguggccuaacccuuguggagggagccgucgaaggug ggaucggcgauugggacgaagucguaacaagguagccguaccggaaggug cggcuggaucaccuc .....<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<< <.<<<..<<<..<<.<..<<<<<<<....>>>>>.>>>..>>>>>..... .<<........<<<<<<<..<<...<<<<<<<<<<<<.....<<<<<<.. ..>>>>>>......>>>>.....<<<<<<<<<<<<..>>>>>.>>>>>>> ....<<....>>>>>>>>>>..>>>>>>>>>.<<<....<<<..<<<<<< <<.......>>>>>>>>>>>......>>>..<<<<<<<<....>>>>... >>>>.>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>> >>.........<<<....<<<<....>>>>..>>>..>>.>>>>>>..<< <<......<<<<....>>>>.....>>>>...<.<<<<<......<<... .>>.......>>>>>....>..<<<<<(((...<<<<<.....<<.)))> >.......>>>>>>>>>>..>>>>>>>>>..........<<<((.....< <<<...<<<.<<<<<<<.<<<<<<<<<<.....<<<<<<<.....>>>>> >>...>>>>>>>..>>>>>>>>>>...<<<<<<<<...<<<<<<<....< <<<<<<<<..<<<......>>>.....>>>>>>>>>...........<<. ...>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....<<<<<<... <<...<<<<.<.....>.>>>>...>>>>>>>>..........<<<<<<. .<<<<<<<<<<<<.......>>>>>>>>>>>>...<<..))>>.....>> >>>>.>>>.<<<......<<<<....>>>>....>>>..)))).]<<<<< .<<<<<<<.<<.<<<<<<..<<<<<<<<<<......<<........>>.. ........<<<<<<<......<<<<<<<...<<<<<<<....>>>>>>>. <<.....>>.>>>>>>>.<<<.<<<..<<<<<<.......<<<<<<<<<. ...>>>..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<.... <<..<<<......>>>>>.....>>>>>>.....<<<<<.....>>>>>. .......>>>>.........>>>...>>>>>>>>>...>>>>>>>...>> .>>>>>>>>.....<<<<<<<.....<<<..<<..<<<<....>>>>..> >....>>>......>>>>>>>......<....<<<<<<<........>>> >>>>....>.....>>>>>>....<<<<<<<..........>>>>>>>.. ....>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<< ..<<<<....<.<<<<..<<<..<<.....>>.>>>.>>>>.>...>>>> ..>>>>>>..>>>.>>>>..>.>>...>.....<<<<<<<<<....>>>> >>>>>..........

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 8wib Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH. Resolution 3.5 Å Binding residue (original residue number in PDB) P2 T3 Q5 Q6 R9 K10 R12 R13 D14 K15 S27 P28 Q29 R30 R31 K43 K44 N46 S47 A48 L49 R50 K51 T58 G69 E70 G84 K88 D89 R94 R110 K111 Q112 A113 R114 S115 R116 K120 K121 Binding residue (residue number reindexed from 1) P1 T2 Q4 Q5 R8 K9 R11 R12 D13 K14 S26 P27 Q28 R29 R30 K42 K43 N45 S46 A47 L48 R49 K50 T57 G68 E69 G83 K87 D88 R93 R109 K110 Q111 A112 R113 S114 R115 K119 K120

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0000049 tRNA binding GO:0003735 structural constituent of ribosome GO:0019843 rRNA binding

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome
GO:0015935	small ribosomal subunit
GO:1990904	ribonucleoprotein complex

View graph for Molecular Function

View graph for Biological Process

View graph for Cellular Component