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Structure of PDB 8wi9 Chain h Binding Site BS01

Receptor Information >8wi9 Chain h (length=153) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] PRKGPAPKRPLVNDPVYGSQLVTQLVNKVLLEGKKSLAERIVYGALEQAR EKTGTDPVVTLKRALDNVKPALEVRSRRVGGATYQVPVEVRPDRSTTLAL RWLVNFSRQRREKTMVERLANEILDASNGLGASVKRREDTHKMAEANRAF AHY

Ligand information >8wi9 Chain a (length=1515) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] uggagaguuugauccuggcucaggacgaacgcuggcggcgugcuuaacac augcaagucgaacggaaaggcccuuucggggguacucgaguggcgaacgg gugaguaacacgugggugaucugcccugcacuuugggauaagccugggaa acugggucuaauaccgaauacacccugcuggucgcauggccugguagggg aaagcuuuugcggugugggaugggcccgcggccuaucagcuuguuggugg ggugauggccuaccaaggcgacgacggguagccggccugagagggugacc ggccacacugggacugagauacggcccagacuccuacgggaggcagcagu ggggaauauugcacaaugggcgcaagccugaugcagcgacgccgcgugag ggaugacggccuucggguuguaaaccucuuucagcacagacgaagcgcaa gugacgguaugugcagaagaaggaccggccaacuacgugccagcagccgc gguaauacguaggguccgagcguuguccggaauuacugggcguaaagagc ucguaggugguuugucgcguuguucgugaaaacucacagcuuaacugugg gcgugcgggcgauacgggcagacuagaguacugcaggggagacuggaauu ccugguguagcgguggaaugcgcagauaucaggaggaacaccgguggcga aggcgggucucugggcaguaacugacgcugaggagcgaaagcguggggag cgaacaggauuagauacccugguaguccacgccguaaacgguggguacua gguguggguuuccuuccuugggauccgugccguagcuaacgcauuaagua ccccgccuggggaguacggccgcaaggcuaaaacucaaaggaauugacgg gggcccgcacaagcggcggagcauguggauuaauucgaugcaacgcgaag aaccuuaccuggguuugacaugcacaggacgccggcagagaugucgguuc ccuuguggccugugugcagguggugcauggcugucgucagcucgugucgu gagauguuggguuaagucccgcaacgagcgcaacccuugucucauguugc cagcacguuaugguggggacucgugagagacugccggggucaacucggag gaagguggggaugacgucaagucaucaugccccuuauguccagggcuuca cacaugcuacaauggccgguacaaagggcugcgaugccgugagguggagc gaauccuuucaaagccggucucaguucggaucggggucugcaacucgacc ccgugaagucggagucgcuaguaaucgcagaucagcaacgcugcggugaa uacguucccgggccuuguacacaccgcccgucacgucaugaaagucggua acacccgaagccgguggccuaacccuuguggagggagccgucgaaggugg gaucggcgauugggacgaagucguaacaagguagccguaccggaaggugc ggcuggaucaccucc ....<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<<< .<<<..<<<..<<.<..<<<<<<<....>>>>>.>>>..>>>>>...... <<........<<<<<<<..<<...<<<<<<<<<<<<.....<<<<<<... .>>>>>>......>>>>.....<<<<<<<<<<<<..>>>>>.>>>>>>>. ...<<....>>>>>>>>>>..>>>>>>>>>.<<<....<<<..<<<<<<< <.......>>>>>>>>>>>......>>>..<<<<<<<<....>>>>...> >>>.>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>>> >.........<<<....<<<<....>>>>..>>>..>>.>>>>>>..<<< <......<<<<....>>>>.....>>>>...<.<<<<<......<<.... >>.......>>>>>....>..<<<<<(((...<<<<<.....<<.)))>> .......>>>>>>>>>>..>>>>>>>>>..........<<<((.....<< <<...<<<.<<<<<<<.<<<<<<<<<<.....<<<<<<<.....>>>>>> >...>>>>>>>..>>>>>>>>>>...<<<<<<<<...<<<<<<<....<< <<<<<<<..<<<......>>>.....>>>>>>>>>...........<<.. ..>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....<<<<<<...< <...<<<<.<.....>.>>>>...>>>>>>>>..........<<<<<<.. <<<<<<<<<<<<.......>>>>>>>>>>>>...<<..))>>.....>>> >>>.>>>.<<<......<<<<....>>>>....>>>..)))).]<<<<<. <<<<<<<.<<.<<<<<<..<<<<<<<<<<......<<........>>... .......<<<<<<<......<<<<<<<...<<<<<<<....>>>>>>>.< <.....>>.>>>>>>>.<<<.<<<..<<<<<<.......<<<<<<<<<.. ..>>>..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<....< <..<<<......>>>>>.....>>>>>>.....<<<<<.....>>>>>.. ......>>>>.........>>>...>>>>>>>>>...>>>>>>>...>>. >>>>>>>>.....<<<<<<<.....<<<..<<..<<<<....>>>>..>> ....>>>......>>>>>>>......<....<<<<<<<........>>>> >>>....>.....>>>>>>....<<<<<<<..........>>>>>>>... ...>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<<. .<<<<....<.<<<<..<<<..<<.....>>.>>>.>>>>.>...>>>>. .>>>>>>..>>>.>>>>..>.>>...>.....<<<<<<<<<....>>>>> >>>>...........

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 8wi9 Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH. Resolution 3.5 Å Binding residue (original residue number in PDB) P2 R3 K4 P6 A7 R10 N28 E33 G34 K35 K36 L38 R41 R79 T98 R102 R109 K114 M116 Binding residue (residue number reindexed from 1) P1 R2 K3 P5 A6 R9 N27 E32 G33 K34 K35 L37 R40 R78 T97 R101 R108 K113 M115

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0000049 tRNA binding GO:0003723 RNA binding GO:0003729 mRNA binding GO:0003735 structural constituent of ribosome GO:0019843 rRNA binding

	Biological Process
GO:0000028	ribosomal small subunit assembly
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome
GO:0015935	small ribosomal subunit
GO:0022627	cytosolic small ribosomal subunit
GO:1990904	ribonucleoprotein complex

View graph for Molecular Function

View graph for Biological Process

View graph for Cellular Component