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Structure of PDB 8wi9 Chain e Binding Site BS01

Receptor Information >8wi9 Chain e (length=200) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] ARYTGPATRKSRRLGVDLVGGDQSFEKRPYPPGQHGRARIKESEYRQQLQ EKQKARFSYGVMEKQFRRYYEEANRQPGKTGDNLLRILESRLDNVVYRAG LARTRRMARQLVSHGHFLVNGVKVDIPSYRVSQYDIIDVKEKSLNTLPFQ IARETAGERPIPSWLQVVGERQRILVHQLPERAQIDVPLTEQLIVELYSK

Ligand information >8wi9 Chain a (length=1515) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] uggagaguuugauccuggcucaggacgaacgcuggcggcgugcuuaacac augcaagucgaacggaaaggcccuuucggggguacucgaguggcgaacgg gugaguaacacgugggugaucugcccugcacuuugggauaagccugggaa acugggucuaauaccgaauacacccugcuggucgcauggccugguagggg aaagcuuuugcggugugggaugggcccgcggccuaucagcuuguuggugg ggugauggccuaccaaggcgacgacggguagccggccugagagggugacc ggccacacugggacugagauacggcccagacuccuacgggaggcagcagu ggggaauauugcacaaugggcgcaagccugaugcagcgacgccgcgugag ggaugacggccuucggguuguaaaccucuuucagcacagacgaagcgcaa gugacgguaugugcagaagaaggaccggccaacuacgugccagcagccgc gguaauacguaggguccgagcguuguccggaauuacugggcguaaagagc ucguaggugguuugucgcguuguucgugaaaacucacagcuuaacugugg gcgugcgggcgauacgggcagacuagaguacugcaggggagacuggaauu ccugguguagcgguggaaugcgcagauaucaggaggaacaccgguggcga aggcgggucucugggcaguaacugacgcugaggagcgaaagcguggggag cgaacaggauuagauacccugguaguccacgccguaaacgguggguacua gguguggguuuccuuccuugggauccgugccguagcuaacgcauuaagua ccccgccuggggaguacggccgcaaggcuaaaacucaaaggaauugacgg gggcccgcacaagcggcggagcauguggauuaauucgaugcaacgcgaag aaccuuaccuggguuugacaugcacaggacgccggcagagaugucgguuc ccuuguggccugugugcagguggugcauggcugucgucagcucgugucgu gagauguuggguuaagucccgcaacgagcgcaacccuugucucauguugc cagcacguuaugguggggacucgugagagacugccggggucaacucggag gaagguggggaugacgucaagucaucaugccccuuauguccagggcuuca cacaugcuacaauggccgguacaaagggcugcgaugccgugagguggagc gaauccuuucaaagccggucucaguucggaucggggucugcaacucgacc ccgugaagucggagucgcuaguaaucgcagaucagcaacgcugcggugaa uacguucccgggccuuguacacaccgcccgucacgucaugaaagucggua acacccgaagccgguggccuaacccuuguggagggagccgucgaaggugg gaucggcgauugggacgaagucguaacaagguagccguaccggaaggugc ggcuggaucaccucc ....<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<<.....<<< .<<<..<<<..<<.<..<<<<<<<....>>>>>.>>>..>>>>>...... <<........<<<<<<<..<<...<<<<<<<<<<<<.....<<<<<<... .>>>>>>......>>>>.....<<<<<<<<<<<<..>>>>>.>>>>>>>. ...<<....>>>>>>>>>>..>>>>>>>>>.<<<....<<<..<<<<<<< <.......>>>>>>>>>>>......>>>..<<<<<<<<....>>>>...> >>>.>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>>> >.........<<<....<<<<....>>>>..>>>..>>.>>>>>>..<<< <......<<<<....>>>>.....>>>>...<.<<<<<......<<.... >>.......>>>>>....>..<<<<<(((...<<<<<.....<<.)))>> .......>>>>>>>>>>..>>>>>>>>>..........<<<((.....<< <<...<<<.<<<<<<<.<<<<<<<<<<.....<<<<<<<.....>>>>>> >...>>>>>>>..>>>>>>>>>>...<<<<<<<<...<<<<<<<....<< <<<<<<<..<<<......>>>.....>>>>>>>>>...........<<.. ..>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....<<<<<<...< <...<<<<.<.....>.>>>>...>>>>>>>>..........<<<<<<.. <<<<<<<<<<<<.......>>>>>>>>>>>>...<<..))>>.....>>> >>>.>>>.<<<......<<<<....>>>>....>>>..)))).]<<<<<. <<<<<<<.<<.<<<<<<..<<<<<<<<<<......<<........>>... .......<<<<<<<......<<<<<<<...<<<<<<<....>>>>>>>.< <.....>>.>>>>>>>.<<<.<<<..<<<<<<.......<<<<<<<<<.. ..>>>..<<<<......>>>>..>>>>>>.....<<<<.<<<<<<....< <..<<<......>>>>>.....>>>>>>.....<<<<<.....>>>>>.. ......>>>>.........>>>...>>>>>>>>>...>>>>>>>...>>. >>>>>>>>.....<<<<<<<.....<<<..<<..<<<<....>>>>..>> ....>>>......>>>>>>>......<....<<<<<<<........>>>> >>>....>.....>>>>>>....<<<<<<<..........>>>>>>>... ...>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<<<<<<. .<<<<....<.<<<<..<<<..<<.....>>.>>>.>>>>.>...>>>>. .>>>>>>..>>>.>>>>..>.>>...>.....<<<<<<<<<....>>>>> >>>>...........

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 8wi9 Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH. Resolution 3.5 Å Binding residue (original residue number in PDB) A2 R3 P7 T9 R10 R13 R14 R29 G34 Q35 H36 K42 Y46 L50 K53 Q54 M63 E64 K65 Q66 R69 N75 R76 R104 T105 R107 R110 Q111 S114 H115 H117 K124 I127 S129 Y130 K143 P149 E197 K201 Binding residue (residue number reindexed from 1) A1 R2 P6 T8 R9 R12 R13 R28 G33 Q34 H35 K41 Y45 L49 K52 Q53 M62 E63 K64 Q65 R68 N74 R75 R103 T104 R106 R109 Q110 S113 H114 H116 K123 I126 S128 Y129 K142 P148 E196 K200

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0003723 RNA binding GO:0003735 structural constituent of ribosome GO:0019843 rRNA binding

	Biological Process
GO:0006412	translation
GO:0042274	ribosomal small subunit biogenesis

	Cellular Component
GO:0005840	ribosome
GO:0015935	small ribosomal subunit
GO:1990904	ribonucleoprotein complex

View graph for Molecular Function

View graph for Biological Process

View graph for Cellular Component