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Structure of PDB 8wkp Chain S11P Binding Site BS01

Receptor Information >8wkp Chain S11P (length=128) Species: 330779 (Sulfolobus acidocaldarius DSM 639) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] REIRWGNARIYASQNNTIITITDITGAEIISKASGGMVVKADREKPSPYA AMLAANKAANDAFDKGISAIHIKVRAQGGYGSKTPGPGAQPAIRALARAG FIIGRIEDVTPLPHDTIRRPGGRRGRRV

Ligand information >8wkp Chain A16S (length=1325) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] auuccgguugauccugccggacccgaccgcuaucgggguagggauaagcc augggagucuuacacucccggguaagggaguguggcggacggcugaguaa cacguggcuaaccuacccucgggacggggauaaccccgggaaacugggga uaauccccgauagggaaggaguccuggaaugguuccuucccuaaagggcu auaggcuauuucccguuuguagcgcccgaggauggggcuacggcccauca ggcugucggugggguaaaggcccaccgaaccuauaacggguaggggccgu ggaagcgggagccuccaguugggcacugagacaagggcccaggcccuacg gggcgcaccaggcgcgaaacguccccaaugcgcgaaagcgugagggcgcu accccgagugccuccgcaggaggcuuuuccccgcucuaaaaaggcggggg aauaagcggggggcaagucuggugucagccgccgcgguaauaccagcucc gcgaguggucggggugauuacugggccuaaagcgccuguagccggcccac caagucgccccuuaaaguccccggcucaaccggggaacugggggcgauac uggugggcuagggggcgggagaggcgggggguacucccggaguaggggcg aaauccuuagauaccgggaggaccaccaguggcggaagcgccccgcuaga acgcgcccgacggugagaggcgaaagccgggggucccggcuguaaacgau gcgggcuaggugucgaguaggcuuagagccuacucggugccgcagggaag ccguuaagcccgccgccuggggaguacggucgcaagacugaaacuuaaag gaauuggcgggggagcaccacaagggguggaaccugcggcucaauuggag ucaacgccuggaaucuuaccggggagaccgcaguaugacggccaggcuaa cgaccuugccugacucgcggagaggaggugcauggccgucgccagcucgu guugugaaauguccgguuaaguccggcaacgagcgagacccccaccccua guugguauucuggacuccgguccagaaccacacuagggggacugccggcg uaagccggaggaaggagggggccacggcaggucagcaugccccgaaaccg ggccgcacgcggguuacaauggcagggacaacgggaugcuaccucgaaag ggggagccaauccuuaaacccugccgcaguugggaucgagggcugaaacc cgcccucgugaacgaggaaucccuaguaaccgcgggucaacaacccgcgg ugaauacgucccugcuccuugcaca ...<<<<<.[.((((>>>>>.<<<<<<<<......<<<.<<......<<< .<<<...<...<<<<<<<<......>>>>>>>>.>......<<<...... ..<<<<<<<..<<...<<<<<<<.<<<<.....<<<<........>>>>. .....>>>>...<<<<<<.<<.<<......>>>>.>>>>>>........< <<................>>>...>>>>>>>..>>>>>>>>>.<<<.... <<....<<<<<<<.......>>>>>>>..>>......>>>..<<<<<<<< ....>>>>...>>>>.>>><<<<<............>>>>>.<<<<.... >>>>...>>>>>>.........<<<....<<<<....>>>>..>>>..>> ..>>>....<<<<<.....>>>>>...<<<<<<<.........>>>>>>> .....<<<<<((......<<<<.....<<..))>>.......>>>>.>>> >>...>>>>>>>>..........<<<((.....<<<<...<<<.<<<<<< <.<<<<<<<<<......<<<<<<<.....>>>>>>>....>>>>>>>..> >>>>>>>>...<<<<<<.....<<<<<<<<<<.<<<<<<<....<<.... ....>>.......>>>>>>>.>>>.......<<....>>.>>>>>>>... .>>>.>>>...>>>...>>>>...<<<<<<.....>>>>>>......... <<<<<<..<<<.<<<<<<.<<<.....>>>.>>>>>>.>>>...<<..)) >>.....>>>>>>.>>>.<<<......<<<<....>>>>....>>>..)) )).].<.....<<<<<...<<.<<<<<..<<.<<<<<<<.......<<.. ......>>..........<<<...................<<.<<<.... ...>>>.>>..............<<.<<....<<<<<.......<<<<<< ............<<<<......>>>>..>>>>>>....<<<...<<<<<< <..........<<<<....>>>>.........>>>>>>>.....<<<<<. ...>>>>>.........>>>.........>>>...>>..>>>>.....>> >....>.>>>>>>>>.....<<<.<<<.......<..<...<<<<....> >>>...>....>......>>>.>>>...........<<<<<<<....... .>>>>>>>...........>>>>>....<<<<<<<<.......>>>>>>> >......>>....>>>>>...>...

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 8wkp Structural basis of translation inhibition by a valine tRNA-derived fragment Resolution 4.62 Å Binding residue (original residue number in PDB) R13 Y15 N19 N20 T21 I22 G30 A31 E32 I33 I34 S35 K36 S38 G40 M41 D46 R47 K49 K77 R79 G83 Y84 P115 L116 P117 H118 D119 T120 I121 R122 R130 Binding residue (residue number reindexed from 1) R9 Y11 N15 N16 T17 I18 G26 A27 E28 I29 I30 S31 K32 S34 G36 M37 D42 R43 K45 K73 R75 G79 Y80 P111 L112 P113 H114 D115 T116 I117 R118 R126

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0003735 structural constituent of ribosome GO:0019843 rRNA binding

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome
GO:0022627	cytosolic small ribosomal subunit
GO:1990904	ribonucleoprotein complex

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