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BioLiP

Structure of PDB 8zjd Chain R Binding Site BS01

Receptor Information
>8zjd Chain R (length=285) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AWLVPLFFAALMLLGLVGNSLVIYVICRHKPMRTVTNFYIANLAATDVTF
LLCCVPFTALLYPLPGWVLGDFMCKFVNYIQQVSVQATCWTLTAMSVDRW
YVTVFPLRALHRRTPRLALAVSLSIWVGSAAVSAPVLALHRLSPGPRAYC
SEAFPSRALERAFALYNLLALYLLPLLATCACYAAMLRHLGRVSALQGQV
LAERAGAVRAKVSRLVAAVVLLFAACWGPIQLFLVLQALGPWHPRSYAAY
ALKTWAHCMSYSNSALNPLLYAFLGSHFRQAFRRV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8zjd Cryo-EM structure of kisspeptin receptor bound to KP-10
Resolution3.06 Å
Binding residue
(original residue number in PDB)		F98 L101 L102 L105 P106 G107 V118 N119 Q122 Q123 V126 F204 N208 I279 L283 R297 Y299 Y302 K305 H309
Binding residue
(residue number reindexed from 1)		F57 L60 L61 L64 P65 G66 V77 N78 Q81 Q82 V85 F163 N167 I230 L234 R245 Y247 Y250 K253 H257
External links
PDB RCSB:8zjd, PDBe:8zjd, PDBj:8zjd
PDBsum8zjd
PubMed
UniProtQ969F8|KISSR_HUMAN KiSS-1 receptor (Gene Name=KISS1R)

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