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Structure of PDB 2fk0 Chain Q Binding Site BS01

Receptor Information >2fk0 Chain Q (length=322) Species: 284218 (Influenza A virus (A/Viet Nam/1203/2004(H5N1))) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] GDQICIGYHANNSTEQVDTIMEKNVTVTHAQDILEKKHNGKLCDLDGVKP LILRDCSVAGWLLGNPMCDEFINVPEWSYIVEKANPVNDLCYPGDFNDYE ELKHLLSRINHFEKIQIIPKSSWSSHEASLGVSSACPYQGKSSFFRNVVW LIKKNSTYPTIKRSYNNTNQEDLLVLWGIHHPNDAAEQTKLYQNPTTYIS VGTSTLNQRLVPRIATRSKVNGQSGRMEFFWTILKPNDAINFESNGNFIA PEYAYKIVKKGDSTIMKSELEYGNCNTKCQTPMGAINSSMPFHNIHPLTI GECPKYVKSNRLVLATGLRNSP

Ligand information Ligand ID BMA InChI InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5+,6-/m1/s1 InChIKey WQZGKKKJIJFFOK-RWOPYEJCSA-N SMILES Software SMILES CACTVS 3.341 OC[C@H]1O[C@@H](O)[C@@H](O)[C@@H](O)[C@@H]1O OpenEye OEToolkits 1.5.0 C(C1C(C(C(C(O1)O)O)O)O)O CACTVS 3.341 OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O OpenEye OEToolkits 1.5.0 C([C@@H]1[C@H]([C@@H]([C@@H]([C@@H](O1)O)O)O)O)O ACDLabs 10.04 OC1C(O)C(OC(O)C1O)CO Formula C6 H12 O6 Name beta-D-mannopyranose; beta-D-mannose; D-mannose; mannose ChEMBL DrugBank ZINC ZINC000003830679 PDB chain 2fk0 Chain X Residue 3 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 2fk0 Structure and Receptor Specificity of the Hemagglutinin from an H5N1 Influenza Virus. Resolution 2.95 Å Binding residue (original residue number in PDB) D53 G55 V56 K57 N276 N278 Binding residue (residue number reindexed from 1) D44 G47 V48 K49 N274 N276 Annotation score 4

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0046789 host cell surface receptor binding

	Biological Process
GO:0019064	fusion of virus membrane with host plasma membrane

	Cellular Component
GO:0019031	viral envelope

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