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Structure of PDB 8whx Chain N Binding Site BS01

Receptor Information >8whx Chain N (length=122) Species: 246196 (Mycolicibacterium smegmatis MC2 155) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] MIQQESRLKVADNTGAKEILCIRVLGGSSRRYAGIGDVIVATVKDAIPGG NVKRGDVVKAVVVRTVKERRRADGSYIKFDENAAVIIKNDNDPRGTRIFG PVGRELREKKFMKIVSLAPEVL

Ligand information >8whx Chain A (length=3020) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] aaguguuuaagggcgcaugguggaugccuuggcacugggagccgaugaag gacguaggaggcugcgauaagccucggggagcugucaaccgagcguugau ccgaggauguccgaauggggaaacccggcacgagugaugucgugucacca ggcgcugaauauauaggcgucuggggggaacgcggggaagugaaacaucu caguacccguaggaagagaaaacaaaaugugauuccgugaguaguggcga gcgaaagcggaggauggcuaaaccguaugcaugugauaccggguaggggu ugugugugcgggguugugggaccuaucuuuccggcucuaccuggcuggag ggcagugagaaaauguugugguuagcggaaauggcuugggauggccugcc guagacggugagagcccgguacgugaaaacccgacgucugucuugauggu guucccgaguagcagcgggcccguggaaucugcugugaaucugccgggac cacccgguaagccugaauacuucccagugaccgauagcggauuaguaccg ugagggaauggugaaaaguaccccgggaggggagugaaagaguaccugaa accgugcgcuuacaauccgucagagcccucgacgugucguggggugaugg cgugccuuuugaagaaugagccugcgagucagggacaugucgcgagguua acccgggugggguagccgcagcgaaagcgagucugaauagggcguaucca cacaagagugugugguguagugguguguucuggacccgaagcggagugau cuacccauggccagggugaagcgcggguaagaccgcguggaggcccgaac ccacuuagguugaagacugaggggaugagcuguggguaggggugaaaggc caaucaaacuccgugauagcugguucuccccgaaaugcauuuaggugcag cgucgcauguuucuugccggagguagagcuacuggauggccgaugggccc cacaggguuacugacgucagccaaacuccgaaugccgguaaguccaagag ugcggcagugagacggcgggggauaagcuccgugcgucgagagggaaaca gcccagaucgccggcuaaggccccuaagcgugugcuaaguggaaaaggau gugcagucgcgaagacaacuggucaagugauugugcgccgauaauguagc ggggcucaagcacaccgccgaagccgcggcagccaacguguuggcugggu aggggagcguccugcauccggugaagccgccgagugaucgagugguggag ggugugggagugagaaugcaggcaugaguagcgauuaggcaagugagaac cuugcccgccgaaagaccaaggguuccugggccaggccaguccgcccagg gugagucgggaccuaaggcgaggccgacaggcguagucgauggacaacgg guugauauucccguacccguguaugugcguccaugaugaaucagcgguac uaaccauccggcugcaugggaccuucguugguaguagucaagcgaugggg ugacgcaggaagguagccguaccggucagugguaauaccgggguaagccu guagggagucagauagguaaauccgucuggcauauauccugagaggugau gcauagccgagugaggcgaauucggugauccuaugcugccgagaaaagcc ucuagcgaggacauacacggcccguaccccaaaccaacacagguggucag guagagaauacuaaggcguacgagugaacuaugguuaaggaacucggcaa aaugcccccguaacuucgggagaagggggacccacauggcguguaagccu uuacggcccaagcgugaguggguggcacaaaccagugagaagcgacuguu uacuaaaaacacagguccgugcgaagucgcaagacgauguauacggacug acgccugcccggugcuggaagguuaagaggacccguuaacucccuuuggg ggugaagcggagaauuuaagccccaguaaacggcggugguaacuauaacc auccuaagguagcgaaauuccuugucggguaaguuccgaccugcacgaau ggcguaacgacuucucaacugucucaaccauagacucggcgaaauugcac uacgaguaaagaugcucguuacgcgcggcaggacgaaaagaccccgggac cuucacuacaacuugguauuggugcucgauacgguuuguguaggauaggu gggagacugugaagcucacacgccaguguggguggagucguuguugaaau accacucugaucguauugggccucuaaccucggaccguauauccgguuca gggacagugccugguggguaguuuaacuggggcgguugccuccuaaaaug uaacggaggcgcccaaagguucccucaaccuggacggcaaucagguguug aguguaagugcacaagggagcuugacugcgagacggacaugucgagcagg gacgaaagucgggacuagugauccggcaccucugaguggaaggggugucg cucaacggauaaaagguaccccggggauaacaggcugaucuuccccaaga gaucgacgggaugguuuggcaccucgaugucggcucgucgcauccugggg cuggagcaggucccaaggguugggcuguucgcccauuaaagcggcacgcg agcuggguuuagaacgucgugagacaguucggucucuauccgccgcgcgc gucagaagcuugaggaaaccugucccuaguacgagaggaccgggacggac gaaccucugguauaccaguugucccaccaggggcacggcuggauagccac guucggacaggauaaccgcugaaagcaucuaagcgggaaaccucuuccaa gaccaggcuucucacccucuaggagggauaaggccccccgcagaccacgg gauugauagaccagaccuggaagccuaguaauaggugcagggaacuggca cuaaccggccgaaaacuuac <<<<......<<<<<<<<<<<.....<<..<<<<<<<<<<<<<......< <<<<<.[[.(((.>>>.....<<<<<<<..<<<)))..]].>>>.....> >>>>>>...>>>....<<<....>>><<<<<<<......>>>>>>>.<<< <<<<<<.........>>>>>>>>>.>>...<<<<<<.....<<....>>. .....>>>>>.>.........<<.....>>..<<<<<<.....<<..... >>....>>>>>>...<<<....<<<<<<<<<<.........(((((.... .>>>>>>>>>>......<<<<<.<.....<<<<<<<))))).>>>>>>>< <<<<<.......<<<<<<.<<<<.<<<.....<<<<......>>>>.((. .....<<<.....))>>>...>>>...>>>>>>>>>>>>>>>>.....>. >.>>>>.....<<<<<<<<.........>>>>>>>>......<<<<<..< <<<>>>>>..>>>......>>.>>>>>>>.>>...............<<. ...>>....>>.........<<<<....>>>>.................. >>>>>>>>>>>.......<<<<..<<<<<<<<<..>>>>.>>>>>..>>> >...<.<........>.>.<<<<<<....<<<.<<<<<<<<<<..<<<.. .<<<....>>>...>>>...<<....>>..<<<<.....>>>>....<<< <<<<....>>>>>>>....>>>>>>>>>>>>>..<<.<..<<<<<<<... ..<<<<<<<<<..<<<....<<<<<<......>>>>>>.....>>>...< <<.<<<<<........>>>>>>>>....>>>>>>>>>...<<<.....>> >......>>>>>>...>..>.>>..<<<<<<....<<<<<....>>>>>< <<<<<<<<....<<<<<<<<.....<<<....<<<.<.<<......<<<< ....>>>>.......>>.>.>>>..>>.>.....>>>>>>>>.......> >>>>>>.>>..<<<<<<<<<<......>>>>>>.>>>>....<<<..... .>>>...<<<<.<<<...<<<(((.....<<<<<<...........<<.. <<<<<<<<<........<<..>>....>>>>>>>>>.>>........... )))......>>>>>>.>>>...>>>>>>><<<<<<<<..>>>>>>>>... .>>>>>>..<<<<<<<<<<......<<<<<<<<....>>>.>>>>>...> >>>>>>>>>........>>>>>><......<<.....<<<<<<....... >>>>>><<<<....<<<<<.<<...<<<<<<...<<.....>>.>>>>>> ....((<<<<.<<...<<<...<<<....>>>...>>>...>>...<<<< <........>>>>>))<<<<<<<<<<.......<<<<...<<<<<<<... ...<<<<<.....>.>>>>.....>>>>>>>.....>>>>.<<...<<<< <...<<<<..<<<..<<<<..<<<<<...((((...>>>>>.<<..<<<< ...<<<<<<<<<<<.<<.....>>>>>>>>>.....>>>>...>>>>... >>...<<<......>>>.....>>>>...>>>...>>>>........>>> >>..>>....>>>>>>>>>>>>>>..>>.....<<......>>>>>>>.< <<<.....>>>>..>>>>..<<<<<...<<<<<<<<.<<.........<. ....<<<<<....<<..>>.....>>>>><<<<<<...<<<<....<<<. ....>>>....>>>>..>>>>>>............<<<<<<<<<..<<<. ........>>>..<<<<<<<.....<<<....>>>.......>>>>>>>. <<<<<.<<<..<<<<<<<..<<<...<<....<<<<..<<<<<<...>>> >>>...>>>>....>>...>>>>>>>>..>>>>><<<<<<.......>>> >>>........<...........<<<<<<.....>>>>>>.....>.... >>>>>..>>.>>>>>>>..>..>>.>>>>>>>>>>>>>>>.....>.((. .<<<<<......))>>>>>..<<<<<<<<.<<<.<<......<<<<<<<< <<..<<<<<.<<<.<<<<<.<<.<<<<<<<<<<<...............< <<..<<<......<<<<<<<<....>>>>>>>>...>>>........... .>>>......>>>>>>>>>>>.>>...<<<.<<<<<<......>>>>>>> >>....>>>>>.>>>..>>>>>..<<<<.....>>>><<<<<<....... ....>>>>>>..<<...<<<<<<<...<<<<<<.......>>>>>>.... .<<.[.(((>>....>>>>>>>...<<<<..<<<<....>>>>..>>>>. <<<....>>>.>>)))]......<<<<<<<.<<..>>>>..>>>>>>>>> .............>>>>..>>>>>>.......<<<<...<.<<<<...<< ..>>...>>>>.>....>>>.>.......<<<<<.<<<<<<..<<<<<<< <<......>>>>>>..>>>.<<<<<.....>>>>>.....>>>>>..>.. .>>>.>>....<<<<<<<....>>>.>>>>....>>..>>>>>>>>>>>. ...<<<<<<<...<<<<..<<<<<<<...............>>>>>>>.< <<<<...<<<<...<<<<<<<<<<<))))>>>>>>..>>>>>...>>>>. >>>>>...<<<....<<<<<...........>>>>>....>>>.>>>>.. .....>>>>>>>..<<<<<...>>>>>....<<<<.<<<<.......>>> >.....<<<.<<<<.<<<....<<<<<....>>>>>...>>>..>>>>.. >>>...>>>>....>>>>..

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 8whx Cryo- EM structure of the mycobacterial 70S ribosome in complex with ribosome hibernation promotion factor RafH. Resolution 2.8 Å Binding residue (original residue number in PDB) M1 Q3 E5 S6 R7 I22 R23 S28 S29 R30 R31 Y32 K44 K67 E68 Y76 Binding residue (residue number reindexed from 1) M1 Q3 E5 S6 R7 I22 R23 S28 S29 R30 R31 Y32 K44 K67 E68 Y76

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0003735 structural constituent of ribosome GO:0019843 rRNA binding GO:0070180 large ribosomal subunit rRNA binding

	Biological Process
GO:0006412	translation

	Cellular Component
GO:0005840	ribosome
GO:0015934	large ribosomal subunit
GO:0022625	cytosolic large ribosomal subunit
GO:1990904	ribonucleoprotein complex

View graph for Molecular Function

View graph for Biological Process

View graph for Cellular Component