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Structure of PDB 6psr Chain L Binding Site BS01

Receptor Information >6psr Chain L (length=548) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure] SQLKLLVTRGKEQGYLTYAEVNDHLPEDIVDSDQIEDIIQMINDMGIQVM EELMLAENTADEDAAEAAAQVLSSVESEIGRTTDPVRMYMREMGTVELLT REGEIDIAKRIEDGINQVQCSVAEYPEAITYLLEQYDRVEAEEARLSDLI TGFVDPELAREKFAELRAQYVVTRDTIATAQEEILKLSEVFKQFRLVPKQ FDYLVNSMRVMMDRVRTQERLIMKLCVEQCKMPKKNFITLFTGNETSDTW FNAAIAMNKPWSEKLHDVSEEVHRALQKLQQIEEETGLTIEQVKDINRRM SIGEAKARRAKKEMVEANLRLVISIAKKYTNRGLQFLDLIQEGNIGLMKA VDKFEYRRGYKFSTYATWWIRQAITRSIADQARTIRIPVHMIETINKLNR ISRQMLQEMGREPTPEELAERMLMPEDKIRKVLKIAKEPISMETPIGDDE DSHLGDFIEDTTLELPLDSATTESLRAATHDVLAGLTAREAKVLRMRFGI DMNTDYTLEEVGKQFDVTRERIRQIEAKALRKLRHPSRSEVLRSFLDD

Ligand information >6psr Chain O (length=36) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure] gcacaaatccattgacaaaagaaggctaaaagggca

Receptor-Ligand Complex Structure Global view Local view Structure summary [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] [Spin on] [Spin off] [Reset] [High quality] [Low quality] [White background] [Black background] PDB 6psr Stepwise Promoter Melting by Bacterial RNA Polymerase. Resolution 3.4 Å Binding residue (original residue number in PDB) R423 Y430 W433 R451 P453 R554 V582 T583 R586 Q589 Binding residue (residue number reindexed from 1) R358 Y365 W368 R386 P388 R489 V517 T518 R521 Q524

Enzymatic activity Enzyme Commision number ?

Gene Ontology Molecular Function GO:0003677 DNA binding GO:0003700 DNA-binding transcription factor activity GO:0005515 protein binding GO:0016987 sigma factor activity

	Biological Process
GO:0006351	DNA-templated transcription
GO:0006352	DNA-templated transcription initiation
GO:0006355	regulation of DNA-templated transcription
GO:0009408	response to heat
GO:0010468	regulation of gene expression
GO:0045892	negative regulation of DNA-templated transcription
GO:2000142	regulation of DNA-templated transcription initiation

	Cellular Component
GO:0000345	cytosolic DNA-directed RNA polymerase complex
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:1903865	sigma factor antagonist complex

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