BioLiP

Structure of PDB 2iuo Chain H Binding Site BS01

Receptor Information

>2iuo Chain H (length=156) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MIQSQINRNIRLDLADAILLSKAKKDLSFAEIADGTGLAEAFVTAALLGQ
QALPADAARLVGAKLDLDEDSILLLQMIPLRGCIDDRIPTDPTMYRFYEM
LQVYGTTLKALVHEKFGDGIIGAINFKLDVKKVADPEGGERAVITLDGKY
LPTKPF

Ligand information

Ligand ID

InChI

InChI=1S/ClH/h1H/p-1

InChIKey

VEXZGXHMUGYJMC-UHFFFAOYSA-M

SMILES

Software	SMILES
ACDLabs 10.04 CACTVS 3.341 OpenEye OEToolkits 1.5.0	[Cl-]

Formula

Name

CHLORIDE ION

PDB chain

2iuo Chain H Residue 1158 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	2iuo Structure of Cyanase Reveals that a Novel Dimeric and Decameric Arrangement of Subunits is Required for Formation of the Enzyme Active Site.
Resolution	1.9 Å
Binding residue (original residue number in PDB)	G122 I124
Binding residue (residue number reindexed from 1)	G122 I124
Annotation score	1

Enzymatic activity

Catalytic site (original residue number in PDB)	R96 E99 G122
Catalytic site (residue number reindexed from 1)	R96 E99 G122
Enzyme Commision number	4.2.1.104: cyanase.

Gene Ontology

	Molecular Function
GO:0003677	DNA binding
GO:0008824	cyanate hydratase activity
GO:0016829	lyase activity

	Biological Process
GO:0009439	cyanate metabolic process
GO:0009440	cyanate catabolic process

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Molecular Function

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Biological Process

PDB	RCSB:2iuo, PDBe:2iuo, PDBj:2iuo
PDBsum	2iuo
PubMed
UniProt	P00816\|CYNS_ECOLI Cyanate hydratase (Gene Name=cynS)