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BioLiP

Structure of PDB 5ts1 Chain G Binding Site BS01

Receptor Information
>5ts1 Chain G (length=273) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PHSLRYFVTAVSRPGLGEPRFIAVGYVDDTQFVRFDSDADNPRFEPRAPW
MEQEGPEYWEEQTQRAKSDEQWFRVSLRTAQRYYNQSKGGSHTFQRMFGC
DVGSDWRLLRGYHQFAYDGRDYIALNEDLKTWTAADTAALITRRKWEQAG
DAEYYRAYLEGECVEWLRRYLELGNETLLRTDSPKAHVTYHPRSQVDVTL
RCWALGFYPADITLTWQLNGEDLTQDMELVETRPAGDGTFQKWAAVVVPL
GKEQNYTCHVHHKGLPEPLTLRW
Ligand information
>5ts1 Chain S (length=9) Species: 83332 (Mycobacterium tuberculosis H37Rv) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
YYQSGLSIV
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB5ts1 MHC-restricted Ag85B-specific CD8+T cells are enhanced by recombinant BCG prime and DNA boost immunization in mice.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		Y7 V9 F45 Q63 R66 D70 W73 V76 S77 T80 Y84 R97 T143 K146 W147 D152 Y155 Y156 Y159 E163 W167 Y171
Binding residue
(residue number reindexed from 1)		Y6 V8 F44 Q62 R65 D69 W72 V75 S76 T79 Y83 R96 T142 K145 W146 D151 Y154 Y155 Y158 E162 W166 Y170
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:5ts1, PDBe:5ts1, PDBj:5ts1
PDBsum5ts1
PubMed31135967
UniProtP01902|HA1D_MOUSE H-2 class I histocompatibility antigen, K-D alpha chain (Gene Name=H2-K1)

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